Randomized controlled clinical trial of acupuncture treatment for knee osteoarthritis in the early stage
Bibliographic record
Abstract
Objective To observe the therapeutic effect of acupuncture in the treatment of patients with knee osteoarthritis(KOA)in the early stage.Methods A total of 60 KOA patients were randomized into medication group and acupuncture combined with medication(acupuncture)group(n=30 in each group).Patients of the medication group were treated by external application of Diclofenac Diethylamine Emulgel around the affected joint,3 times a day for 2 successive weeks and reasonable exercising training.Patients of the acupuncture group received routine medication and reasonable exercising training and acupuncture of Ashi-points,Zusanli(ST36),Yanglingquan(GB34),Yinlingquan(SP9),Neixiyan(EX-LE4)and Dubi(ST35)at affected side with filiform needles which were manipulated with uniform reinforcing-reducing method for a while,followed by retaining the needles for 30 min.The treatment was conducted once every other day for 2 weeks.The pain degree was assessed by using visual analog scale(VAS)and the Western Ontario McMaster Universities Osteoarthritis Index(WOMAC)scale(0-240 points)was used to evaluate the severity of KOA,and the"Diagnosis of Syndromes of Traditional Chinese Medicine"was used to assess the therapeutic effect after the treatment.Results After the treatment,the VAS and WOMAC scores of both medication and acupuncture groups were significantly and respectively decreased in comparison with their own pre-treatment(P<0.05),and the scores of the two indexes of the acupuncture group were evidently lower than those of the medication group(P<0.05).Of the two 30 cases in the medication and acupuncture groups,5(16.67%)and 6(20.00%)were cured,17(56.67%)and 19(63.33%)experienced marked improvement,6(20.00%)and 4(13.33%)were effective,2(6.67%)and 1(3.33%)were ineffective,with the effective rate of cure plus marked effectiveness being 73.33% and 83.33%,respectively.No significant difference was found between the two groups in the therapeutic effect(P>0.05).Conclusion Acupuncture combined with medication has a better therapeutic effect in the treatment of KOA in the early stage than that of the simple medication.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.004 | 0.004 |
| Meta-epidemiology (narrow) | 0.002 | 0.001 |
| Meta-epidemiology (broad) | 0.009 | 0.002 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.002 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.003 | 0.003 |
| Insufficient payload (model declined to judge) | 0.012 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".