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Record W7163882316 · doi:10.52843/cassyni.kx424m

Transradial versus Transfemoral Neuroangiography in a Tertiary Pediatric Hospital – a Propensity Score Matched Study

2025· article· W7163882316 on OpenAlexaff
Kevin Fung, Jamie Ho, Suzanne Bickford, Vanessa Rea, Will Lee, C Parra-Farinas, Marc Ayoub, Prakash Muthusami

Bibliographic record

Venuenot available
Typearticle
Language
FieldMedicine
TopicVascular Procedures and Complications
Canadian institutionsSickKids FoundationHospital for Sick Children
Fundersnot available
KeywordsPropensity score matchingVasospasmFluoroscopyNeurovascular bundleRetrospective cohort studyRadial arteryHematomaAsymptomatic

Abstract

fetched live from OpenAlex

## Introduction To evaluate the feasibility and safety of transradial access (TRA) in comparison to transfemoral access (TFA) for pediatric neurovascular procedures. ## Materials and Methods Retrospective cohort study including 729 pediatric neurovascular procedures performed between January 2020 and December 2024, with 175 TRAs and 540 TFAs. Primary outcomes included technical success and adverse events, while secondary outcomes assessed radiation dose, fluoroscopy time and procedural duration. Propensity score matching (1:1) was applied to adjust for imbalance in baseline covariates. Statistical significance was set at P<.05. ## Results 100 matched pairs of TRA and TFA were analyzed (TRA median age 13.9 [IQR 11.7–15.3] years, 52 females; TFA median age 14.5 [IQR 11.6–16.4] years, 51 females). Technical success rates were similar between TRA and TFA (98% vs 99%, P >.99). TRA was associated with a higher rate of vasospasm (7% vs 1%, P=.03) and a lower rate of hematoma formation (2% vs 9%, P=.03). Fluoroscopy time was longer in the TRA group (19.4 vs 8.8 minutes, P <0.001), but the radiation dose and procedural time were comparable between both groups. Asymptomatic radial artery occlusion (RAO) was detected in 5.1% (9/175) of radial accesses. A sheath-to-artery (S/A) ratio ≥1 was independently associated with RAO (OR 6.13; 95% CI:1.32-28.4; P=.021). ## Discussion TRA is a technically feasible and safe alternative to TFA for pediatric neurovascular procedures. Although vasospasm is more frequent, TRA reduces hematoma risk and offers comparable procedural outcomes. Pre-procedural US assessment of radial artery and optimization of S/A ratio are important to reducing the risk of RAO.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.018
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.004
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.266
Teacher spread0.241 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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