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Record W7163884445 · doi:10.52843/cassyni.mmsjwv

Femoral Arterial Access in Pediatric Diagnostic Angiography and Endovascular Interventions: Predictors of Technical Success, Adverse Events and Thrombotic Risk

2025· article· W7163884445 on OpenAlexaff
Kevin Fung, Aisling Carroll-Downey, A Gasparetto, C Parra-Farinas, Dimitri Parra, Joao Amaral, Marc Ayoub, Prakash Muthusami

Bibliographic record

Venuenot available
Typearticle
Language
FieldMedicine
TopicVascular Procedures and Complications
Canadian institutionsSickKids FoundationHospital for Sick Children
Fundersnot available
KeywordsHematomaThrombosisAdverse effectRetrospective cohort studyAngiographyLogistic regressionVasospasmVascular access

Abstract

fetched live from OpenAlex

## Introduction To identify predictors of technical success and adverse events (AEs) associated with ultrasound (US)-guided femoral arterial (FA) access in children undergoing diagnostic angiography and interventions. ## Materials and Methods Retrospective study including consecutive FA access attempts aged ≤18 years at a tertiary pediatric hospital between January 2018 and December 2024. Baseline demographics, corrected FA diameter and technical details were analysed using univariable and multivariable Firth logistic regression to identify predictors of technical success and AEs. ## Results 661 US-guided FA access were attempted in 311 patients. Median age was 7.9 years (range, 0.09–17.9), and median corrected FA diameter was 4.6 mm (range, 1.2–9.6). 49.8% (329/661) accesses were for interventions. Technical success was 99.2% (656/661). The overall AE rate was 5.4% (36/661), with 1.7% (11/661) SIR moderate and severe grades. Vasospasm, more common in arteries ≤3.9 mm, was associated with both access failure and thrombosis. Prophylactic intra-arterial nitroglycerin significantly reduced vasospasm risk (P < .001). Arterial thrombosis occurred in 0.9% (6/661) of accesses, with median age of 0.3 years, weight of 6.4 kg and corrected FA diameter of 1.7mm. All cases were managed anticoagulation, with no permanent ischemic sequelae. Independent predictors of thrombosis included sheath-to-artery (S/A) ratio ≥1 (P<.001) and use of vascular closure device (VCD) (P=.02). Hematoma was associated with ≥6 French sheath and body weight ≥75 kg (P<.001). ## Discussion US-guided FA access has a high success and low AE rate in children. Pre-procedural US assessment, careful sheath selection and prophylactic intra-arterial nitroglycerin can help improve outcome. VCD should be used with caution in children.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.013
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.002
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.299
Teacher spread0.286 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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