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Record W71933752 · doi:10.1089/aid.2013.0274

Toward an Endgame: Finding and Engaging People Unaware of Their HIV-1 Infection in Treatment and Prevention

2014· review· en· W71933752 on OpenAlexfundno aff
David Burns, Victor DeGruttola, Christopher D. Pilcher, Mirjam Kretzschmar, Christopher M. Gordon, Elizabeth Flanagan, Christopher Duncombe, Myron S. Cohen

Bibliographic record

VenueAIDS Research and Human Retroviruses · 2014
Typereview
Languageen
FieldMedicine
TopicHIV/AIDS Research and Interventions
Canadian institutionsnot available
FundersNational Institute of Allergy and Infectious DiseasesNational Institute of Mental HealthRijksinstituut voor Volksgezondheid en MilieuU.S. Public Health ServiceCenters for Disease Control and PreventionPublic Health EnglandUniversity of WashingtonImperial College LondonHarvard UniversityJohns Hopkins UniversityBill and Melinda Gates FoundationWake Forest UniversityEmory UniversityNational Institute on Drug AbuseYork UniversityUniversity of North Carolina at Chapel HillGeorge Washington UniversityNational Institutes of HealthU.S. Department of Health and Human Services
KeywordsChess endgameHuman immunodeficiency virus (HIV)MedicineTreatment as preventionIncidence (geometry)Antiretroviral treatmentAntiretroviral therapyImmunologyIntensive care medicineFamily medicineViral loadComputer science

Abstract

fetched live from OpenAlex

Epidemic modeling suggests that a major scale-up in HIV treatment could have a dramatic impact on HIV incidence. This has led both researchers and policymakers to set a goal of an "AIDS-Free Generation." One of the greatest obstacles to achieving this objective is the number of people with undiagnosed HIV infection. Despite recent innovations, new research strategies are needed to identify, engage, and successfully treat people who are unaware of their infection.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.924
Threshold uncertainty score0.929

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0020.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.245
GPT teacher head0.486
Teacher spread0.241 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designOther design
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations40
Published2014
Admission routes1
Has abstractyes

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