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Resistant Starch reduces postprandial glycemic and insulinemic response and increases satiety in humans

2009· article· en· W76337037 on OpenAlexaff
Cyril W.C. Kendall, Amin Esfahani, Lisa Sanders, Susan Potter, David J.A. Jenkins

Bibliographic record

VenueThe FASEB Journal · 2009
Typearticle
Languageen
FieldMedicine
TopicNutritional Studies and Diet
Canadian institutionsMuscular Dystrophy CanadaUniversity of Toronto
Fundersnot available
KeywordsPostprandialCrossover studyAppetiteGlycemicMealMedicineInsulinGlycemic indexInternal medicineEndocrinology

Abstract

fetched live from OpenAlex

Objective To assess the dose‐response effect of adding resistant starch to drinks on postprandial glycemia, insulinemia, satiety and post‐load ad libitum food intake. Methods 22 healthy "unrestrained eaters" (13 male, 9 female, age 26±4y; BMI 23.7±2.4kg/m ² ) consumed meals containing 0g, 5g, 15g and 25g of PROMITOR(tm) RS in a randomized, double blind, crossover study. Using a visual analogue scale (VAS), subjects rated their satiety level and symptoms at 0, 15, 30, 45, 60, 90 and 120 min after eating. Blood samples were taken simultaneously. Using the satiety ratings, the satiety quotient and appetite score were calculated. Two hours after eating, subjects were given an ad libitum meal and total energy intake was recorded. Results All meals were well tolerated and no significant adverse symptoms were reported. Compared to the control, the 25g dose of RS resulted in significantly lower blood glucose (P≤0.002) and serum insulin levels at 90min and 120 min. In addition the satiety quotient for mean appetite score for the 25g RS dose was significantly higher (P≤0.05) compared to the control at 15min and 45 min. However second meal ad libitum meal total energy intake was not different between treatments. Conclusions The inclusion of RS may effectively reduce the postprandial glycemic and insulinemic response of meals and increase satiety without adverse symptoms.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.280
Teacher spread0.262 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2009
Admission routes1
Has abstractyes

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