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Record W810803440

Contextual determinants of chronic diseases: cardiovascular disease and cancer

2014· dissertation· en· W810803440 on OpenAlexaboutno aff
Ayesha Rana

Bibliographic record

VenueMacSphere (McMaster University) · 2014
Typedissertation
Languageen
FieldMedicine
TopicGDF15 and Related Biomarkers
Canadian institutionsnot available
Fundersnot available
KeywordsCancerDiseaseMedicineInternal medicine
DOInot available

Abstract

fetched live from OpenAlex

Background: In Canada, cardiovascular disease (CVD) and cancer are the leading causes of mortality and morbidity in adults. Research in health geography has established the importance of contextual factors (e.g., community nutrition, and physical activity environments) as significant contributors to CVD and cancer. Objectives: The objectives of this project are to: 1) systematically review the Canadian literature on the effects of contextual exposures on chronic diseases (CVD and cancer); 2) develop a method of assessment of measuring key contextual factors; and 3) explore the variations in contextual characteristics of urban and rural areas using the pilot data collected by a Canada-wide cohort study (CVCD Alliance). Methods: Objective (1): MEDLINE, EMBASE, and CINAHL databases, and reference list of articles were searched from inception through Jan 20, 2014. English language human studies, conducted in Canada, that relate to contextual factors/built environment and chronic diseases were eligible for inclusion. Objective (2): EPOCH-1 was modified to correspond with definition of community used in CVCD. Mean agreement was calculated to measure the reliability of the modified EPOCH-1. Objective (3): Physical activity (walkscore) and nutrition (cost of food basket) environments of urban and rural areas were compared using t-test. Results: Objective (1): Review of the literature indicated that fewer fast food outlets, increased density of destinations and higher socio-economic status were associated with positive health outcomes. Objective (2): Mean agreement between raters of modified EPOCH-1 was excellent (close to 0). Objective (3): Analysis of pilot data showed that as compared to urban areas, there was a trend towards higher food costs and lower walkability in rural areas. However, this trend was not statistically significant (p>0.05). Conclusion: This project will add to the current understanding of the impact of contextual characteristics on health, and promote the development of new interventions that aim to change modifiable environmental exposures.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.952
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0080.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.217
Teacher spread0.209 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designOther design
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2014
Admission routes1
Has abstractyes

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