Bibliographic record
Abstract
The incretin hormone, glucagon-like peptide-1 (GLP-1) serves as a link between ingested nutrients and insulin secretion. Because of the anti-diabetic properties exerted by GLP-1, several derivative drugs are currently in the market for the treatment of patients with type 2 diabetes. Over the past few years, several cell lines have been established as useful models for the study of the GLP-1-secreting enteroendocrine L-cells. This review focuses on the murine GLUTag cell line, derived from colonic tumours of transgenic mice expressing large T antigen under the control of the proglucagon promoter. These cells are widely used to examine the effects of food components on GLP-1 secretion, as well as the signaling pathways underlying nutrient-induced GLP-1 release. The effects of different food components, as well as of nutrient-related signals, on GLP-1 secretion, and the protocols for the maintenance and use of the murine GLUTag L-cell line will be discussed.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.002 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".