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Record W830811084

Material Properties of Antibiotic Releasing Contact Lenses

2014· article· en· W830811084 on OpenAlexaffabout
Alex Hui, Lyndon Jones

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldMedicine
TopicOcular Surface and Contact Lens
Canadian institutionsUniversity of Waterloo
Fundersnot available
KeywordsLens (geology)Contact lensMaterials scienceContact angleWettingOpticsFocal lengthScleral lensSessile drop techniqueComposite material
DOInot available

Abstract

fetched live from OpenAlex

Acknowledgements Determination of Material Properties water content, wet and dry weight, light transmission, centre thickness, surface wettability The water content and wet and dry weight of lenses was determined using the gravimetric method (Sartorius MA 100, Sartorius Canada Inc, Mississauga, Ontario), where the change in weight as the lens was heated to 105°C over the course of 7 minutes was correlated to the water content of the lens. The centre thickness of a fully hydrated lens was measured using a contact lens thickness gauge (Vigor Contact Lens Thickness Gauge, Vigor Optical, Carlstadt, New Jersey). To determine the light transmission, individual lenses and 1 mL of phosphate buffered saline (PBS) were placed into wells of a 24 well plate, and a wavelength scan from 300 nm to 750 nm was conducted using a plate reader (Spectramax M5 Microplate reader, Molecular Devices, Sunnyvale, California). The advancing contact angle, a measure of the surface wettability, was determined using the sessile drop method employing the Optical Contact Analyzer (OCA, Dataphysics Instruments GmbH, Filderstadt, Germany). A fully hydrated lens was removed from the PBS soaking solution, and the surface dried on lens paper for 20 seconds before being placed on a custom designed lens holder. 5 μL of High Performance Liquid Chromatography water was dispensed from a syringe, and an image of the contact of the water droplet with the lens surface after settling captured using a high speed camera. The contact angle between the settled drop and the lens surface was analyzed using custom software (SCA 20 software, Version 2.04, Build 4).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.005
Threshold uncertainty score0.016

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0050.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.228
Teacher spread0.210 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2014
Admission routes2
Has abstractyes

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