MétaCan
Menu
Back to cohort
Record W85917427 · doi:10.1093/pch/15.4.226

Paediatric myasthenia: A moving target

2010· article· en· W85917427 on OpenAlexaff
Hanna Kolski, Jiri Vajsar, Danielle Grenier

Bibliographic record

VenuePaediatrics & Child Health · 2010
Typearticle
Languageen
FieldMedicine
TopicMyasthenia Gravis and Thymoma
Canadian institutionsCanadian Paediatric SocietyHospital for Sick ChildrenStollery Children's HospitalUniversity of Alberta
Fundersnot available
KeywordsMedicineMyasthenia gravisInternal medicine

Abstract

fetched live from OpenAlex

A two-and-a-half-year-old boy presented to the emergency department with an upper respiratory tract infection and increasing breathing difficulties over the past 24 h. His health was normal until two months before presentation. Since then, his parents noticed progressive (although fluctuating) motor weakness, trouble chewing and swallowing as well as episodes of choking on his secretions. His speech deteriorated to monosyllables, and he had trouble walking and getting up off the floor. The boy's ‘tired-ness’ seemed substantially more noticeable in the evenings. A physical examination of the boy revealed moderate respiratory distress. Otherwise, the only remarkable physical signs included bilateral asymmetrical ptosis (his right eye appeared to be more affected than his left eye), and decreased facial movements with the inability to close his eyes and with his mouth hanging open. He was generally weak, hypotonic and could not rise from a lying position. His deep tendon reflexes were preserved. On admission, his respiratory status deteriorated to the point of requiring intubation for five days. A diagnosis of respiratory syncytial virus pneumonia was confirmed. Although his respiratory status improved, his weakness remained. Diagnostic evaluations included high acetyl-cholinesterase antibodies and a positive edrophonium test, resulting in transient reversal of the ptosis.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Editorial · Consensus signal: none
Teacher disagreement score0.004
Threshold uncertainty score0.015

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0010.002
Open science0.0010.001
Research integrity0.0040.003
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.259
Teacher spread0.250 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEditorial

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2010
Admission routes1
Has abstractyes

Explore more

Same venuePaediatrics & Child HealthSame topicMyasthenia Gravis and ThymomaFrench-language works237,207