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The Effect of Whey Protein on Post‐Meal Blood Glucose and Insulin

2009· article· en· W90062543 on OpenAlexaffabout
Tina Akhavan, Bohdan L. Luhovyy, Harvey Anderson

Bibliographic record

VenueThe FASEB Journal · 2009
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicMuscle metabolism and nutrition
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsMealInsulinWhey proteinIngestionInternal medicineFood scienceChemistryEndocrinologyMedicine

Abstract

fetched live from OpenAlex

Dairy protein ingestion is associated with satiety and the reduction of blood glucose (BG) in response to carbohydrate. The objective of this experiment was to examine the effect of whey protein on pre‐ and post‐meal glucose and insulin. Healthy normal weight adult males (n = 10) and females (n = 8) were provided whey protein (5, 10, 20 and 40 g) and hydrolyzed whey protein (10 g) in 300 ml of water or water alone 30 min prior to a pizza meal (12 kcal/kg body weight). Insulin and BG were measured by finger prick at baseline and at intervals pre‐and post‐meal for 170 min. Pre‐ (0‐30 min) and post‐ (30‐170 min) meal areas under the curve (AUCs) for BG and insulin were calculated. Sex (p <0.05) and whey protein (p <0.001) affected BG and insulin responses. Females had higher post‐meal BG and insulin AUCs than males (n =18, p < 0.05). Whey protein (10 g to 40 g) increased pre‐meal insulin and BG but reduced post‐meal BG and insulin AUCs (n = 18, p <0.05). The lower post‐meal BG AUC after whey protein was not associated with a higher insulin AUC compared with the control suggesting that whey protein treatments improved post‐meal insulin sensitivity. We concluded that the ingestion of whey protein prior to a meal resulted in lower post‐meal BG and insulin and reduced the amount of insulin required for the post‐meal glucose response. Grant Funding Source Natural Sciences and Engineering Research Council of Canada (NSERC) and Kraft Ins.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.003

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.004
GPT teacher head0.215
Teacher spread0.211 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2009
Admission routes2
Has abstractyes

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