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Record W91676723

Investigating the vector competence of the house fly (Musca domestica) for Campylobacter jejuni

2014· dissertation· en· W91676723 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

fundA Canadian funder is recorded on the work.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueSummit (Simon Fraser University) · 2014
Typedissertation
Languageen
FieldAgricultural and Biological Sciences
TopicInsect Utilization and Effects
Canadian institutionsnot available
FundersGrønt Udviklings- og Demonstrations ProgramDanmarks Frie ForskningsfondNatural Sciences and Engineering Research Council of CanadaCanada Research ChairsInternationalt Center for Forskning i Økologisk Jordbrug og Fødevaresystemer
KeywordsMuscaCampylobacter jejuniBiologyOn the flyCompetence (human resources)MicrobiologyComputer scienceEcologyGeneticsPsychologyBacteria
DOInot available

Abstract

fetched live from OpenAlex

Campylobacteriosis is a severe gastroenteric disease in humans caused by the bacterium, Campylobacter jejuni, typically obtained through the ingestion of contaminated poultry products. Poultry facilities become contaminated through the introduction of pathogens, including C. jejuni, by the house fly, Musca domestica. This thesis investigates the vector competence of M. domestica for C. jejuni to determine if the bacteria survive house fly metamorphosis from larva to adult, and can multiply within adult flies to enhance transmission, and whether innate immune factors of the house fly can clear C. jejuni infections. We demonstrate that M. domestica mounts an effective innate immune response that prevents transmission of C. jejuni from larva to adult, and eliminates C. jejuni from adult house fly gastrointestinal tracts within hours. We propose that M. domestica serves as a mechanical vector, rather than as a true, amplifying, biological vector. These findings will help elucidate the elusive epidemiology of campylobacteriosis.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.473
Threshold uncertainty score0.919

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.202
Teacher spread0.188 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it