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Record W96575948 · doi:10.1289/ehp.112-1277123

Microarray Data Standards: An Open Letter

2004· letter· en· W96575948 on OpenAlexaff
Catherine A. Ball, Alvis Brāzma, Helen C. Causton, Steve Chervitz, Ron Edgar, Pascal Hingamp, John C. Matese, Helen Parkinson, John Quackenbush, Martin Ringwald, Susanna‐Assunta Sansone, Gavin Sherlock, Paul T. Spellman, Christian J. Stoeckert, Yoshio Tateno, Ronald C. Taylor, Joseph White, Neil Winegarden

Bibliographic record

VenueEnvironmental Health Perspectives · 2004
Typeletter
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGene expression and cancer classification
Canadian institutionsUniversity of TorontoUniversity Health Network
Fundersnot available
KeywordsLibrary scienceArt historyClassicsHistoryComputer science

Abstract

fetched live from OpenAlex

What this proposal requires is a change in the way in which we approach the publication of microarray-based studies. Both authors and journals have a responsibility to ensure that the requisite data are available, and because submitting MIAME-compliant data can take considerable time and effort, this process should be factored into review and publication timelines. However, while this process may be time consuming and painful at first, we believe that the benefits of building an open repository of microarray data will far outweigh any initial disadvantages. As always, it is our sincere hope that these suggestions stimulate discussion within the community and that together we can arrive at a consensus that ensures that microarray data are widely and easily accessible. Finally, we would like to urge the DDBJ, EMBL-EBI, and NCBI to work together toward exchanging all MIAME-compliant microarray data.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.037
metaresearch head score (Gemma)0.147
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: Reporting · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.963
Threshold uncertainty score0.195

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0370.147
Meta-epidemiology (narrow)0.0010.002
Meta-epidemiology (broad)0.0020.003
Bibliometrics0.0020.003
Science and technology studies0.0060.008
Scholarly communication0.0090.010
Open science0.0070.004
Research integrity0.0840.065
Insufficient payload (model declined to judge)0.0090.014

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.038
GPT teacher head0.351
Teacher spread0.313 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designNot applicable
DomainReporting
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations23
Published2004
Admission routes1
Has abstractyes

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