The evolving role of natural products in drug discovery
2005· review· en· Nature Reviews Drug Discovery· Medicine
affno abstract
2,555
citations
Works
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10,000+ workspage 17
Acarbose for prevention of type 2 diabetes mellitus: the STOP-NIDDM randomised trial
2002· article· en· The Lancet· Medicine
affno abstract
2,548
citations
Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies
2019· review· en· The Lancet Neurology· Medicine
affno abstract
2,541
citations
Endocrine Regulation of Energy Metabolism by the Skeleton
2007· article· en· Cell· Biochemistry, Genetics and Molecular Biology
affno abstract
2,541
citations
Global carbon dioxide emissions from inland waters
2013· article· en· Nature· Earth and Planetary Sciences
affno abstract
2,541
citations
Pembrolizumab in patients with advanced hepatocellular carcinoma previously treated with sorafenib (KEYNOTE-224): a non-randomised, open-label phase 2 trial
2018· article· en· The Lancet Oncology· Medicine
affno abstract
2,536
citations
Testing the pecking order theory of capital structure
2002· article· en· Journal of Financial Economics· Business, Management and Accounting
affno abstract
2,536
citations
The potential and challenges of nanopore sequencing
2008· review· en· Nature Biotechnology· Engineering
affno abstract
2,533
citations
Defining trained immunity and its role in health and disease
2020· review· en· Nature reviews. Immunology· Immunology and Microbiology
affno abstract
2,527
citations
Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk
2019· review· en· Nature Genetics· Biochemistry, Genetics and Molecular Biology
fundno affno abstract
2,526
citations
Allostatic load biomarkers of chronic stress and impact on health and cognition
2009· review· en· Neuroscience & Biobehavioral Reviews· Neuroscience
affno abstract
2,515
citations
Ground water and climate change
2012· article· en· Nature Climate Change· Earth and Planetary Sciences
affno abstract
2,515
citations
Guidelines for Performing a Comprehensive Transthoracic Echocardiographic Examination in Adults: Recommendations from the American Society of Echocardiography
2018· article· en· Journal of the American Society of Echocardiography· Medicine
aboutno affno abstract
2,502
citations
Progress and problems with the use of viral vectors for gene therapy
2003· review· en· Nature Reviews Genetics· Biochemistry, Genetics and Molecular Biology
fundno affno abstract
2,501
citations
A flat Universe from high-resolution maps of the cosmic microwave background radiation
2000· article· en· Nature· Physics and Astronomy
affno abstract
2,499
citations
Climatological mean and decadal change in surface ocean pCO<sub>2</sub>, and net sea-air CO<sub>2</sub> flux over the global oceans
2009· article· en· HAL (Le Centre pour la Communication Scientifique Directe)· Earth and Planetary Sciences
affno abstract
2,498
citations
Cardiovascular Magnetic Resonance in Myocarditis: A JACC White Paper
2009· article· en· Journal of the American College of Cardiology· Medicine
affno abstract
2,497
citations
Evolution and classification of the CRISPR–Cas systems
2011· review· en· Nature Reviews Microbiology· Biochemistry, Genetics and Molecular Biology
affno abstract
2,496
citations
Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer
2017· article· en· Cell· Medicine
affno abstract
2,495
citations
Glial and neuronal control of brain blood flow
2010· review· en· Nature· Biochemistry, Genetics and Molecular Biology
afffundno abstract
2,492
citations
Association of tumour mutational burden with outcomes in patients with advanced solid tumours treated with pembrolizumab: prospective biomarker analysis of the multicohort, open-label, phase 2 KEYNOTE-158 study
2020· article· en· The Lancet Oncology· Medicine
affno abstract
2,492
citations
Gut–brain axis: how the microbiome influences anxiety and depression
2013· review· en· Trends in Neurosciences· Biochemistry, Genetics and Molecular Biology
affno abstract
2,485
citations
New ICD-10 version of the Charlson comorbidity index predicted in-hospital mortality
2004· article· en· Journal of Clinical Epidemiology· Health Professions
affno abstract
2,484
citations
Genetics of rheumatoid arthritis contributes to biology and drug discovery
2013· review· en· Nature· Medicine
afffundno abstract
2,473
citations
2,469
citations