MétaCan
Menu
Back to cohort
Record W1762846431 · doi:10.1186/s13012-015-0303-4

Using a systematic review in clinical decision making: a pilot parallel, randomized controlled trial

2015· review· en· W1762846431 on OpenAlexafffund
Laure Perrier, Nav Persaud, Kevin E. Thorpe, Sharon E. Straus

Bibliographic record

VenueImplementation Science · 2015
Typereview
Languageen
FieldDecision Sciences
TopicMeta-analysis and systematic reviews
Canadian institutionsSt. Michael's HospitalUniversity of Toronto
FundersCanadian Institutes of Health ResearchUniversity of TorontoWomen's College Hospital
KeywordsMedicineCohen's kappaRandomized controlled trialTest (biology)Clinical trialGold standard (test)Medical physicsScale (ratio)StatisticSystematic reviewFamily medicineMEDLINEMedical educationStatisticsSurgeryPathology

Abstract

fetched live from OpenAlex

BACKGROUND: Evidence suggests that systematic reviews are used infrequently by physicians in clinical decision-making. One proposed solution is to create filtered resources so that information is validated and refined in order to be read quickly. Two shortened systematic review formats were developed to enhance their use in clinical decision-making. METHODS: To prepare for a full-scale trial, we conducted a pilot study to test methods and procedures in order to refine the processes. A recruitment email was sent to physicians practicing full- or part-time in family medicine or general internal medicine. The pilot study took place in an online environment and eligible physicians were randomized to one of the systematic review formats (shortened or full-length) and instructed to read the document. Participants were asked to provide the clinical bottom line and apply the information presented to a clinical scenario. Participants' answers were evaluated independently by two investigators against "gold standard" answers prepared by an expert panel. RESULTS: Fifty-six clinicians completed the pilot study within a 2-month period with a response rate of 4.3 %. Agreement between investigators in assessing participants' answers was determined by calculating a kappa statistic. Two questions were assessed separately, and a kappa statistic was calculated at 1.00 (100 % agreement) for each. CONCLUSIONS: Agreement between investigators in assessing participants' answers is satisfactory. Although recruitment for the pilot study was completed in a reasonable time-frame, response rates were low and will require large numbers of contacts. The results indicate that conducting a full-scale trial is feasible. TRIAL REGISTRATION: ClinicalTrials.gov NCT02414360 .

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.794
metaresearch head score (Gemma)0.476
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Meta-epidemiology (narrow), Meta-epidemiology (broad), Scholarly communication, Open science, Insufficient payload (model declined to judge)
Consensus categoriesMetaresearch, Meta-epidemiology (broad), Insufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Randomized trial · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.533
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.7940.476
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0750.012
Bibliometrics0.0030.010
Science and technology studies0.0000.001
Scholarly communication0.0030.001
Open science0.0070.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0040.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.931
GPT teacher head0.743
Teacher spread0.188 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designRandomized trial
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations9
Published2015
Admission routes2
Has abstractyes

Explore more

Same venueImplementation ScienceSame topicMeta-analysis and systematic reviewsFrench-language works237,207