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Record W1977552244 · doi:10.1021/om049137e

Intermolecular Activation of Hydrocarbon C−H Bonds Initiated by the Tungsten Hydrocarbyl Hydrido Complexes Cp*W(NO)(R)(H)(PMe<sub>3</sub>) (R = Alkyl, Aryl)

2005· article· en· W1977552244 on OpenAlexaff
Kajin Lee, Peter Legzdins, C.B. Pamplin, Brian O. Patrick, Kenji Wada

Bibliographic record

VenueOrganometallics · 2005
Typearticle
Languageen
FieldChemistry
TopicOrganometallic Complex Synthesis and Catalysis
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsChemistryTrimethylphosphineIsomerizationOxidative additionReductive eliminationArylIntramolecular forceStereochemistryBenzeneAlkylMedicinal chemistryCis–trans isomerismCrystal structureCrystallographyCatalysisOrganic chemistry

Abstract

fetched live from OpenAlex

trans -Cp*W(NO)(CH 2 EMe 3 )(H)(PMe 3 ) (E = C, Si) complexes can be prepared by the hydrogenation at 1 atm of the appropriate Cp*W(NO)(CH 2 EMe 3 ) 2 precursor in the presence of a slight excess of PMe 3 . (Our designation of a particular geometrical isomer as cis or trans in this family of complexes indicates the relative positions of the hydrocarbyl and the hydrido ligands in the base of a four-legged piano-stool molecular structure.) The use of D 2 in place of H 2 during these syntheses affords the corresponding trans -Cp*W(NO)(CH 2 EMe 3 )(D)(PMe 3 ) (E = C, Si) complexes. The cis -Cp*W(NO)(CH 2 EMe 3 )(H)(PMe 3 ) isomers are obtainable by C−H bond-activation reactions of the trans precursors. Thus, activation of SiMe 4 by trans -Cp*W(NO)(CH 2 CMe 3 )(H)(PMe 3 ) under ambient conditions produces cis -Cp*W(NO)(CH 2 SiMe 3 )(H)(PMe 3 ). Similarly, activations of C 6 H 6 and C 6 D 6 at 20−27 °C by the trans -Cp*W(NO)(CH 2 EMe 3 )(H)(PMe 3 ) complexes produce cis -Cp*W(NO)(C 6 H 5 )(H)(PMe 3 ) and cis -Cp*W(NO)(C 6 D 5 )(D)(PMe 3 ), respectively, and the solid-state molecular structure of the latter complex has been established by a single-crystal X-ray crystallographic analysis. Kinetic, mechanistic, and theoretical investigations of these benzene C−H activation processes are consistent with initial trans to cis isomerization of the reactants followed by intramolecular reductive elimination of EMe 4 to form the 16-electron Cp*W(NO)(PMe 3 ) intermediate. Subsequent oxidative addition of the incoming benzene substrate to this coordinatively unsaturated intermediate produces the final cis hydrido phenyl complex. These single C−H activation processes are the requisite first steps in the development of these organometallic complexes as catalysts for the selective functionalization of hydrocarbons. All new complexes have been characterized by conventional spectroscopic methods.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.045
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0060.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.212
Teacher spread0.199 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations12
Published2005
Admission routes1
Has abstractyes

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