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Record W2061568914 · doi:10.7326/l15-5075

Models in the Development of Clinical Practice Guidelines

2015· letter· en· W2061568914 on OpenAlexaboutno aff
Ioannis M. Zacharioudakis, Fainareti N. Zervou, Eleftherios Mylonakis

Bibliographic record

VenueAnnals of Internal Medicine · 2015
Typeletter
Languageen
FieldMedicine
TopicClinical practice guidelines implementation
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineGuidelineClinical PracticeObservational studyClinical trialMedical schoolFamily medicineInternal medicineMedical educationPathology

Abstract

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Letters7 April 2015Models in the Development of Clinical Practice GuidelinesIoannis M. Zacharioudakis, MD, Fainareti N. Zervou, MD, and Eleftherios Mylonakis, MD, PhDIoannis M. Zacharioudakis, MDFrom Warren Alpert Medical School of Brown University, Providence, Rhode Island.Search for more papers by this author, Fainareti N. Zervou, MDFrom Warren Alpert Medical School of Brown University, Providence, Rhode Island.Search for more papers by this author, and Eleftherios Mylonakis, MD, PhDFrom Warren Alpert Medical School of Brown University, Providence, Rhode Island.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/L15-5075 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Habbema and colleagues (1) have presented a particularly interesting article about the position of models in clinical practice guidelines. Indeed, models can bridge the gap between direct evidence provided from randomized, controlled trials (RCTs) or observational studies and questions raised in daily practice. To estimate the degree that models are used in the development of current guidelines, we evaluated the list of the 100 most cited guidelines of the National Guideline Clearinghouse (www.guideline.gov) that we had identified for a previous study. The number of citations was extracted from the Thomson Reuters Web of Science (formerly ISI Web ...References1. Habbema JD, Wilt TJ, Etzioni R, Nelson HD, Schechter CB, Lawrence WF, et al. Models in the development of clinical practice guidelines. Ann Intern Med. 2014;161:812-8. [PMID: 25437409] doi:10.7326/M14-0845 LinkGoogle Scholar2. Husereau D, Drummond M, Petrou S, Carswell C, Moher D, Greenberg D, et al; CHEERS Task Force. Consolidated Health Economic Evaluation Reporting Standards (CHEERS) statement. BMJ. 2013;346:f1049. [PMID: 23529982] doi:10.1136/bmj.f1049 CrossrefMedlineGoogle Scholar3. Higgins JP, Altman DG, Gøtzsche PC, Jüni P, Moher D, Oxman AD, et al; Cochrane Bias Methods Group. The Cochrane Collaboration's tool for assessing risk of bias in randomised trials. BMJ. 2011;343:d5928. [PMID: 22008217] doi:10.1136/bmj.d5928 CrossrefMedlineGoogle Scholar4. Wells GA, Shea B, O'Connell D, Peterson J, Welch V, Losos M, et al. The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses. 2014. Accessed at www.ohri.ca/programs/clinical_epidemiology/oxford.asp on 10 December 2014. Google Scholar Author, Article, and Disclosure InformationAffiliations: From Warren Alpert Medical School of Brown University, Providence, Rhode Island.Disclosures: Authors have disclosed no conflicts of interest. Forms can be viewed at www.acponline.org/authors/icmje/ConflictOfInterest Forms.do?msNum=L15-0055. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoModels in the Development of Clinical Practice Guidelines J. Dik F. Habbema , Timothy J. Wilt , Ruth Etzioni , Heidi D. Nelson , Clyde B. Schechter , William F. Lawrence , Joy Melnikow , Karen M. Kuntz , Douglas K. Owens , and Eric J. Feuer Models in the Development of Clinical Practice Guidelines J. Dik F. Habbema , Timothy J. Wilt , Ruth Etzioni , Heidi D. Nelson , Clyde B. Schechter , William F. Lawrence , Joy Melnikow , Karen M. Kuntz , Douglas K. Owens , and Eric J. Feuer Models in the Development of Clinical Practice Guidelines J. Dik F. Habbema , Timothy J. Wilt , and Ruth Etzioni Models in the Development of Clinical Practice Guidelines J. Dik F. Habbema , Timothy J. Wilt , and Ruth Etzioni Metrics Cited ByCollaborative Modeling: Experience of the U.S. Preventive Services Task Force 7 April 2015Volume 162, Issue 7Page: 529-530KeywordsConflicts of interestDisclosureForecastingHealth economicsMathematical modelsObservational studiesReproducibilityTreatment guidelines ePublished: 7 April 2015 Issue Published: 7 April 2015 CopyrightCopyright © 2015 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.023
metaresearch head score (Gemma)0.127
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Research integrity
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.103
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0230.127
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0010.003
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.770
GPT teacher head0.651
Teacher spread0.119 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2015
Admission routes1
Has abstractyes

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