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Record W2075664235 · doi:10.1038/modpathol.2015.38

An international study to increase concordance in Ki67 scoring

2015· article· en· W2075664235 on OpenAlexafffund
Mei‐Yin C. Polley, Samuel Leung, Dongxia Gao, Mauro G. Mastropasqua, Lila Zabaglo, John M.S. Bartlett, Lisa M. McShane, Rebecca A. Enos, Sunil Badve, Anita Bane, Signe Borgquist, Susan Fineberg, Ming-Gang Lin, Allen M. Gown, Dorthe Grabau, Carolina Gutiérrez, Judith Hugh, Takuya Moriya, Yasuyo Ohi, C. Kent Osborne, Frédérique Penault‐Llorca, Tammy Piper, Peggy L. Porter, Takashi Sakatani, Roberto Salgado, Jane Starczynski, Anne‐Vibeke Lænkholm, Giuseppe Viale, Mitch Dowsett, Daniel F. Hayes, Torsten O. Nielsen

Bibliographic record

VenueModern Pathology · 2015
Typearticle
Languageen
FieldMedicine
TopicTraditional Chinese Medicine Studies
Canadian institutionsUniversity of AlbertaJuravinski HospitalMcMaster UniversityOntario Institute for Cancer ResearchUniversity of British Columbia
FundersNational Institute for Health and Care ResearchNIHR Biomedical Research Centre, Royal Marsden NHS Foundation Trust/Institute of Cancer ResearchGovernment of OntarioBreast Cancer Research FoundationPfizerOntario Institute for Cancer ResearchCure Brain Cancer FoundationEli Lilly and Company
KeywordsConcordanceMedicinePathologyMedical physicsInternal medicine

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.020
metaresearch head score (Gemma)0.041
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: Methods · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.980
Threshold uncertainty score0.108

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0200.041
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0030.004
Science and technology studies0.0010.001
Scholarly communication0.0020.001
Open science0.0010.002
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.061
GPT teacher head0.367
Teacher spread0.306 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designObservational
DomainMethods
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations216
Published2015
Admission routes2
Has abstractno

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