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Priority-based initiative for updating existing evidence-based clinical practice guidelines: the results of two iterations

2014· article· en· W2079828477 on OpenAlexaff
Chika Agbassi, Hans Messersmith, Sheila McNair, Melissa Brouwers

Bibliographic record

VenueJournal of Clinical Epidemiology · 2014
Typearticle
Languageen
FieldMedicine
TopicClinical practice guidelines implementation
Canadian institutionsJuravinski HospitalCancer Care OntarioMcMaster University
Fundersnot available
KeywordsGuidelinePrioritizationMedicineQuality of evidenceEvidence-based practiceQuality (philosophy)Evidence-based medicineProcess managementAlternative medicineRandomized controlled trialPathologyBusiness

Abstract

fetched live from OpenAlex

OBJECTIVES: New evidence continues to emerge and requires attention after the release of a clinical practice guideline (CPG). The objective of this article is to describe the Document Assessment and Review (DAR) strategy designed to ensue that the CPGs remain current and their quality maintained and to present the results of two iteration of its implementation. STUDY DESIGN AND SETTING: The DAR process involves an annual assessment of our CPGs and a review of documents that require an update search. Two questionnaires are used to conduct the annual assessment and the review. The review involves evidence search, evidence review, and review approval. RESULTS: In 2011, 109 documents were assessed; 22 (20%) were archived, 1 (1%) was deferred for assessment in 2012, 24 (22%) were considered special cases and 62 (57%) needed a new systematic review of the evidence. Of those 62, 19 (31%) were categorized as urgent, 16 (26%) as high, and others as medium or low priority. In 2012, 88 total documents were assessed; 15 (17%) were archived, 32 (36%) deferred, 3 (3%) were considered special cases, and 38 (43%) were prioritized for review. CONCLUSIONS: Assessment and prioritization of existing CPGs are effective ways of ensuring that resources are directed toward the upkeep of those that are relevant and of highest priority.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Direct model labels (unvalidated)

Per-model category and study-design labels from the labeling rounds. They are machine output, unvalidated, and the disagreement between models ships as data. No study design here is MEDLINE-validated yet.

Model armCategoriesStudy designConfidence
gemmaMetaresearch
Domain: Methods · Genre: Empirical
About the Canadian research system: no · About a Canadian topic: no
Observationallow
gptMetaresearch
Domain: Methods · Genre: Empirical
About the Canadian research system: no · About a Canadian topic: no
Other designlow
models splitAgreement compares identical category sets and study designs across arms.

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.539
metaresearch head score (Gemma)0.498
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesMetaresearch
DomainCandidate signal: Evaluation · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.461
Threshold uncertainty score0.568

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.5390.498
Meta-epidemiology (narrow)0.0020.003
Meta-epidemiology (broad)0.0030.004
Bibliometrics0.0080.006
Science and technology studies0.0060.004
Scholarly communication0.0200.010
Open science0.0070.023
Research integrity0.0080.009
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.856
GPT teacher head0.709
Teacher spread0.147 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Labeled directly by 2 models reading the full record.

Metaresearch

The models disagree on parts of this classification; every voice is preserved in the section at the end of the page.

Study designObservational · Other design
DomainMethods
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations37
Published2014
Admission routes1
Has abstractyes

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