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Record W2084481737 · doi:10.1179/107735209799449770

Chrysotile Biopersistence: The Misuse of Biased Studies

2009· article· en· W2084481737 on OpenAlexaboutno aff
H. Pézerat

Bibliographic record

VenueInternational Journal of Occupational and Environmental Health · 2009
Typearticle
Languageen
FieldMedicine
TopicOccupational and environmental lung diseases
Canadian institutionsnot available
Fundersnot available
KeywordsChrysotileAsbestosMesotheliomaLung cancerEnvironmental healthMedicineToxicologyPathologyBiologyMaterials scienceComposite material

Abstract

fetched live from OpenAlex

Although it is widely accepted that exposure to any asbestos type can increase the likelihood of lung cancer, mesothelioma, and non-malignant lung and pleural disorders, manufacturers and some chrysotile miners' unions contend that chrysotile either does not cause disease or that there is insufficient evidence to reach a conclusion. At the same time, Dr. D.M. Bernstein has published several animal studies, financed by the Québec Chrysotile Institute, to determine chrysotile biopersistence in the lungs. Bernstein's study protocol induces a very short fiber half-life, from which he concludes weak chrysotile carcinogenicity. Bernstein's findings contradict results obtained by independent scientists. Bernstein's results can only be explained by an aggressive pre-treatment of fibers, inducing many faults and fragility in the fibers' structure, leading to rapid hydration and breaking of long fibers in the lungs.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.493
metaresearch head score (Gemma)0.738
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Research integrity
Consensus categoriesMetaresearch
DomainCandidate signal: Methods · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.993
Threshold uncertainty score0.625

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.4930.738
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0040.002
Bibliometrics0.0130.009
Science and technology studies0.0020.012
Scholarly communication0.0090.009
Open science0.0050.007
Research integrity0.0070.008
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.056
GPT teacher head0.382
Teacher spread0.326 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; the direct Gemma label and the distilled Codex classifier agree on what is shown here.

Study designObservational
DomainMethods
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations28
Published2009
Admission routes1
Has abstractyes

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