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Record W2147756241 · doi:10.2106/jbjs.l.00299

Participating in Multicenter Randomized Controlled Trials: What’s the Relative Value?

2012· article· en· W2147756241 on OpenAlexaff
Paul Tornetta, Mandy Pascual, Katelyn Godin, Sheila Sprague, Mohit Bhandari

Bibliographic record

VenueJournal of Bone and Joint Surgery · 2012
Typearticle
Languageen
FieldMedicine
TopicEthics in Clinical Research
Canadian institutionsMcMaster University
Fundersnot available
KeywordsRandomized controlled trialPromotion (chess)IncentiveScale (ratio)Multicenter trialMedicineMulticenter studyValue (mathematics)PsychologyFamily medicineMedical educationPhysical therapyPolitical scienceSurgeryEconomicsComputer scienceGeography

Abstract

fetched live from OpenAlex

The value of high-quality, large-scale, multicenter randomized controlled trials (RCTs) in orthopaedic surgery is becoming well recognized; however, the efforts of investigators participating in RCTs are often underappreciated in areas such as academic merit. Within this manuscript, we discuss how involvement in a large-scale RCT can lead to benefits, such as improvements to clinical practice and decision-making as well as personal incentives. We also examined how investigators' contributions to large multicenter RCTs are perceived and recognized by academic promotion committees. We found that academic promotion committees undervalue contributions to multicenter RCTs as compared with participation in studies that offer lower levels of evidence. The culture of academic promotion needs to evolve to ensure that participation in large multicenter RCTs is appropriately valued by these committees.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.656
metaresearch head score (Gemma)0.885
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesMetaresearch
DomainCandidate signal: Evaluation · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.344
Threshold uncertainty score0.424

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.6560.885
Meta-epidemiology (narrow)0.0020.002
Meta-epidemiology (broad)0.0110.006
Bibliometrics0.0080.011
Science and technology studies0.0040.021
Scholarly communication0.0200.030
Open science0.0070.007
Research integrity0.0210.017
Insufficient payload (model declined to judge)0.0050.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.546
GPT teacher head0.539
Teacher spread0.007 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; the direct Gemma label and the distilled Codex classifier agree on what is shown here.

Study designTheoretical or conceptual
DomainEvaluation
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations13
Published2012
Admission routes1
Has abstractyes

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