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Multi-site assessment of the precision and reproducibility of multiple reaction monitoring–based measurements of proteins in plasma

2009· article· en· 1,037 citations· W2170791918 on OpenAlex· 10.1038/nbt.1546

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.025
GPT teacher head0.318
Teacher spread
0.292 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Nature Biotechnology
Topic
Mass Spectrometry Techniques and Applications
Field
Chemistry
Canadian institutions
University of Victoria
Funders
National Cancer InstituteUniversity of California, San FranciscoU.S. Public Health ServiceCanary Foundation
Keywords
ReproducibilitySelected reaction monitoringTransferabilityBiomarker discoveryBiomarkerMass spectrometryChemistryChromatographyComputational biologyComputer scienceTandem mass spectrometryProteomicsBiologyBiochemistry
Has abstract in OpenAlex
no