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Minimum information about a single amplified genome (MISAG) and a metagenome-assembled genome (MIMAG) of bacteria and archaea

2017· article· en· 2,712 citations· W2745006471 on OpenAlex· 10.1038/nbt.3893

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Abstract

We present two standards developed by the Genomic Standards Consortium (GSC) for reporting bacterial and archaeal genome sequences. Both are extensions of the Minimum Information about Any (x) Sequence (MIxS). The standards are the Minimum Information about a Single Amplified Genome (MISAG) and the Minimum Information about a Metagenome-Assembled Genome (MIMAG), including, but not limited to, assembly quality, and estimates of genome completeness and contamination. These standards can be used in combination with other GSC checklists, including the Minimum Information about a Genome Sequence (MIGS), Minimum Information about a Metagenomic Sequence (MIMS), and Minimum Information about a Marker Gene Sequence (MIMARKS). Community-wide adoption of MISAG and MIMAG will facilitate more robust comparative genomic analyses of bacterial and archaeal diversity.

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The record

Venue
Nature Biotechnology
Topic
Genomics and Phylogenetic Studies
Field
Biochemistry, Genetics and Molecular Biology
Canadian institutions
University of British Columbia
Funders
Lawrence Berkeley National LaboratoryNational Institute of Dental and Craniofacial ResearchNational Institute of Allergy and Infectious DiseasesLaboratory Directed Research and DevelopmentNational Human Genome Research InstituteAustralian Research CouncilNational Institutes of HealthNational Institute of Food and AgricultureRussian Science FoundationJoint Genome InstituteArgonne National LaboratoryU.S. Department of EnergyGordon and Betty Moore FoundationBiotechnology and Biological Sciences Research CouncilOffice of ScienceStiftelsen för Strategisk ForskningU.S. Department of AgricultureUniversity of ChicagoNational Science Foundation
Keywords
MetagenomicsArchaeaGenomeBacteriaBiologyComputational biologyGeneticsBacterial genome sizeBacterial geneticsGeneEscherichia coli
Has abstract in OpenAlex
yes