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Record W2745006471 · doi:10.1038/nbt.3893

Minimum information about a single amplified genome (MISAG) and a metagenome-assembled genome (MIMAG) of bacteria and archaea

2017· article· en· W2745006471 on OpenAlexaff
Robert M. Bowers, Nikos C. Kyrpides, Ramūnas Stepanauskas, Miranda Harmon‐Smith, Devin F. R. Doud, T. B. K. Reddy, Frederik Schulz, Jessica K. Jarett, Adam R. Rivers, Emiley A. Eloe‐Fadrosh, Susannah G. Tringe, Natalia Ivanova, Alex Copeland, Alicia Clum, Eric D. Becraft, Rex R. Malmstrom, Bruce W. Birren, Mircea Podar, Peer Bork, George M. Weinstock, George M Garrity, Jeremy A. Dodsworth, Shibu Yooseph, Granger Sutton, Frank Oliver Glöckner, Jack A. Gilbert, William Nelson, Steven Hallam, Sean P. Jungbluth, Thijs J. G. Ettema, Scott Tighe, Konstantinos T. Konstantinidis, Wen‐Tso Liu, Brett J. Baker, Thomas Rattei, Jonathan A. Eisen, Brian P. Hedlund, Katherine D. McMahon, Noah Fierer, Rob Knight, ROBERT FINN, Guy Cochrane, Ilene Karsch‐Mizrachi, Christian Rinke, Alla Lapidus, Folker Meyer, Pelin Yilmaz, Donovan H. Parks, A. Murat Eren, Lynn M. Schriml, Jillian F. Banfield, Philip Hugenholtz, Tanja Woyke

Bibliographic record

VenueNature Biotechnology · 2017
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenomics and Phylogenetic Studies
Canadian institutionsUniversity of British Columbia
FundersLawrence Berkeley National LaboratoryNational Institute of Dental and Craniofacial ResearchNational Institute of Allergy and Infectious DiseasesLaboratory Directed Research and DevelopmentNational Human Genome Research InstituteAustralian Research CouncilNational Institutes of HealthNational Institute of Food and AgricultureRussian Science FoundationJoint Genome InstituteArgonne National LaboratoryU.S. Department of EnergyGordon and Betty Moore FoundationBiotechnology and Biological Sciences Research CouncilOffice of ScienceStiftelsen för Strategisk ForskningU.S. Department of AgricultureUniversity of ChicagoNational Science Foundation
KeywordsMetagenomicsArchaeaGenomeBacteriaBiologyComputational biologyGeneticsBacterial genome sizeBacterial geneticsGeneEscherichia coli

Abstract

fetched live from OpenAlex

We present two standards developed by the Genomic Standards Consortium (GSC) for reporting bacterial and archaeal genome sequences. Both are extensions of the Minimum Information about Any (x) Sequence (MIxS). The standards are the Minimum Information about a Single Amplified Genome (MISAG) and the Minimum Information about a Metagenome-Assembled Genome (MIMAG), including, but not limited to, assembly quality, and estimates of genome completeness and contamination. These standards can be used in combination with other GSC checklists, including the Minimum Information about a Genome Sequence (MIGS), Minimum Information about a Metagenomic Sequence (MIMS), and Minimum Information about a Marker Gene Sequence (MIMARKS). Community-wide adoption of MISAG and MIMAG will facilitate more robust comparative genomic analyses of bacterial and archaeal diversity.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.016
metaresearch head score (Gemma)0.049
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: Reporting · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.984
Threshold uncertainty score0.082

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0160.049
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0110.007
Science and technology studies0.0010.001
Scholarly communication0.0030.004
Open science0.0030.003
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0070.006

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.230
Teacher spread0.222 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designNot applicable
DomainReporting
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2,712
Published2017
Admission routes1
Has abstractyes

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