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Record W2810636829 · doi:10.1016/j.jalz.2018.05.011

Consent recommendations for research and international data sharing involving persons with dementia

2018· article· en· W2810636829 on OpenAlexafffund
Adrian Thorogood, Anna Mäki‐Petäjä‐Leinonen, Henry Brodaty, Gratien Dalpé, Chris Gastmans, Serge Gauthier, Dianne Gove, Rosie Harding, Bartha Maria Knoppers, Martin N. Rossor, Martin Bobrow

Bibliographic record

VenueAlzheimer s & Dementia · 2018
Typearticle
Languageen
FieldMedicine
TopicEthics in Clinical Research
Canadian institutionsMcGill University
FundersGovernment of CanadaConsortium canadien en neurodégénérescence associée au vieillissementNational Institute for Health and Care ResearchGenome Canada
KeywordsData sharingDementiaHarmonizationInformed consentBest practiceDisciplinePublic relationsPsychologyBusinessEngineering ethicsMedicineKnowledge managementPolitical scienceAlternative medicineComputer scienceLawEngineering

Abstract

fetched live from OpenAlex

Consent is generally required for research and sharing rich individual-level data but presents additional ethical and legal challenges where participants have diminished decision-making capacity. We formed a multi-disciplinary team to develop best practices for consent in data-intensive dementia research. We recommend that consent processes for research and data sharing support decision-making by persons with dementia, protect them from exploitation, and promote the common good. Broad consent designed to endure beyond a loss of capacity and combined with ongoing oversight can best achieve these goals. Persons with dementia should be supported to make decisions and enabled to express their will and preferences about participation in advance of a loss of capacity. Regulatory frameworks should clarify who can act as a representative for research decisions. By promoting harmonization of consent practices across institutions, sectors, and countries, we hope to facilitate data sharing to accelerate progress in dementia research, care, and prevention.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.277
metaresearch head score (Gemma)0.457
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Research integrity
Consensus categoriesMetaresearch
DomainCandidate signal: Methods · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: none
Teacher disagreement score0.966
Threshold uncertainty score0.892

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.2770.457
Meta-epidemiology (narrow)0.0020.003
Meta-epidemiology (broad)0.0020.006
Bibliometrics0.0060.006
Science and technology studies0.0070.010
Scholarly communication0.0080.018
Open science0.0070.009
Research integrity0.0340.029
Insufficient payload (model declined to judge)0.0470.026

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.810
GPT teacher head0.616
Teacher spread0.194 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; the direct Gemma label and the distilled Codex classifier agree on what is shown here.

Study designTheoretical or conceptual
DomainMethods
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations94
Published2018
Admission routes2
Has abstractyes

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