MétaCan
Menu
Back to cohort
Record W2884903472 · doi:10.1101/370874

A randomised controlled trial of an Intervention to Improve Compliance with the ARRIVE guidelines (IICARus)

2018· preprint· en· W2884903472 on OpenAlexaff
Kaitlyn Hair, Malcolm Macleod, David W. Howells, Philip M. Bath, Catriona MacCallum, Gavin Morrison, Alejandra Clark, Gina M. Alvino, Michelle T. Dohm, Jing Liao, Rosie Moreland, Fala Cramond, Gillian L. Currie, Zsanett Bahor, Alexandra Bannach‐Brown, Daniel-Cosmin Marcu, Sarah Antar, Cadi Irvine, Katrina Blazek, Timm Konold, Victoria Hohendorf, Mona Hosh, Klára Z. Gerlei, Kimberley E. Wever, Victor Jones, Terence J. Quinn, Natasha A. Karp, Jennifer Freymann, Anthony Shek, Teja Gregorc, Arianna Rinaldi, Privjyot Jheeta, Ahmed Nazzal, David Henshall, Joanne Storey, Julija Baginskaite, Cilene Lino de Oliveira, Kamil G. Laban, Emmanuel Charbonney, Savannah A. Lynn, Marco Cascella, Emily Wheater, Daniel Baker, Ryan Cheyne, Edward Christopher, Paolo Roncon, Evandro A. De‐Souza, Mahmoud Warda, Sarah Corke, Zeinab Ammar, Leigh O’Connor, Ian M. Devonshire, Emily S. Sena, Sarah McCann, Laura J. Gray, Ezgi Tanriver-Ayder

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2018
Typepreprint
Languageen
FieldVeterinary
TopicAnimal testing and alternatives
Canadian institutionsHôpital du Sacré-Cœur de Montréal
FundersMedical Research CouncilBiotechnology and Biological Sciences Research CouncilDirectorate for Biological SciencesWellcome Trust
KeywordsChecklistGuidelineConsolidated Standards of Reporting TrialsMedicineCompliance (psychology)Intervention (counseling)Randomized controlled trialFamily medicinePsychologyNursingSurgeryPathology

Abstract

fetched live from OpenAlex

Abstract The ARRIVE (Animal Research: Reporting of In Vivo Experiments) guidelines are widely endorsed but compliance is limited. We sought to determine whether journal-requested completion of an ARRIVE checklist improves full compliance with the guidelines. In a randomised controlled trial, manuscripts reporting in vivo animal research submitted to PLOS ONE (March-June 2015) were allocated to either requested completion of an ARRIVE checklist or current standard practice. We measured the change in proportion of manuscripts meeting all ARRIVE guideline checklist items between groups. We randomised 1,689 manuscripts, 1,269 were sent for peer review and 762 accepted for publication. The request to complete an ARRIVE checklist had no effect on full compliance with the ARRIVE guidelines. Details of animal husbandry (ARRIVE sub-item 9a) was the only item to show improved reporting, from 52.1% to 74.1% (X 2 =34.0, df=1, p=2.1×10 −7 ). These results suggest that other approaches are required to secure greater implementation of the ARRIVE guidelines.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Randomized trial · Consensus signal: Randomized trial
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.321
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.104
GPT teacher head0.360
Teacher spread0.256 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designRandomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations23
Published2018
Admission routes1
Has abstractyes

Explore more

Same venuebioRxiv (Cold Spring Harbor Laboratory)Same topicAnimal testing and alternativesFrench-language works237,207