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Record W2887576581 · doi:10.1038/s41431-018-0219-y

Registered access: authorizing data access

2018· article· en· W2887576581 on OpenAlexafffund
Stephanie O. M. Dyke, Mikael Lindén, Ilkka Lappalainen, Jordi Rambla, Knox Carey, David Lloyd, Dylan Spalding, Moran N. Cabili, Giselle Kerry, Julia Foreman, Tim Cutts, Mahsa Shabani, Laura Lyman Rodriguez, Maximilian Haeussler, Brian Walsh, Xiaoqian Jiang, Shuang Wang, Daniel Perrett, Tiffany Boughtwood, Andreas Matern, Anthony J. Brookes, Miro Cupak, Marc Fiume, Ravi Pandya, Ilia Tulchinsky, Serena Scollen, Juha Törnroos, Samir Das, Alan C. Evans, Bradley Malin, Stephan Beck, Steven E. Brenner, Tommi Nyrönen, Niklas Blomberg, Helen V. Firth, Matthew E. Hurles, Anthony Philippakis, Gunnar Rätsch, Michael Brudno, Kym M. Boycott, Heidi L. Rehm, Michael Baudis, Stephen T. Sherry, Bartha Maria Knoppers, Dixie B. Baker, Paul Flicek

Bibliographic record

VenueEuropean Journal of Human Genetics · 2018
Typearticle
Languageen
FieldMedicine
TopicEthics in Clinical Research
Canadian institutionsUniversity of OttawaHospital for Sick ChildrenMontreal Neurological Institute and HospitalUniversity of TorontoOntario GenomicsChildren's Hospital of Eastern OntarioMcGill UniversityMcGill Genome Centre
FundersSpace Operations Mission DirectorateCanadian Institutes of Health ResearchHorizon 2020 Framework ProgrammeVlaamse regeringUniversity College London Hospitals NHS Foundation TrustFonds Wetenschappelijk OnderzoekNational Institutes of HealthGovernment of CanadaNational Human Genome Research InstituteWellcome TrustEuropean Molecular Biology LaboratoryNational Institute for Health and Care ResearchGenome CanadaScience and Technology Facilities CouncilGenomic Health
KeywordsData accessData sharingAccess managementReuseHealth careAllianceComputer scienceBusinessKnowledge managementDatabaseMedicinePolitical scienceComputer network

Abstract

fetched live from OpenAlex

The Global Alliance for Genomics and Health (GA4GH) proposes a data access policy model-"registered access"-to increase and improve access to data requiring an agreement to basic terms and conditions, such as the use of DNA sequence and health data in research. A registered access policy would enable a range of categories of users to gain access, starting with researchers and clinical care professionals. It would also facilitate general use and reuse of data but within the bounds of consent restrictions and other ethical obligations. In piloting registered access with the Scientific Demonstration data sharing projects of GA4GH, we provide additional ethics, policy and technical guidance to facilitate the implementation of this access model in an international setting.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.247
metaresearch head score (Gemma)0.443
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Open science
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.994
Threshold uncertainty score0.928

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.2470.443
Meta-epidemiology (narrow)0.0010.002
Meta-epidemiology (broad)0.0020.003
Bibliometrics0.0050.006
Science and technology studies0.0060.012
Scholarly communication0.0230.036
Open science0.0060.036
Research integrity0.0110.011
Insufficient payload (model declined to judge)0.0610.053

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.856
GPT teacher head0.651
Teacher spread0.205 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designNot applicable
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations48
Published2018
Admission routes2
Has abstractyes

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