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Record W2904384071 · doi:10.1038/nbt.4306

Minimum Information about an Uncultivated Virus Genome (MIUViG)

2018· article· en· W2904384071 on OpenAlexaff
Simon Roux, Evelien M. Adriaenssens, Bas E. Dutilh, Eugene V. Koonin, Andrew M. Kropinski, Mart Krupovìč, Jens H. Kuhn, Rob Lavigne, J. Rodney Brister, Arvind Varsani, Clara Amid, Ramy K. Aziz, Seth R. Bordenstein, Peer Bork, Mya Breitbart, Guy Cochrane, Rebecca A. Daly, Christelle Desnues, Melissa B. Duhaime, Joanne Emerson, François Enault, Jed A. Fuhrman, Pascal Hingamp, Philip Hugenholtz, Bonnie L. Hurwitz, Natalia Ivanova, Jessica Labonté, Kyung-Bum Lee, Rex R. Malmstrom, Manuel Martínez‐García, Ilene Karsch‐Mizrachi, Hiroyuki Ogata, David Páez-Espino, Marie‐Agnès Petit, Catherine Putonti, Thomas Rattei, Alejandro Reyes, Francisco Rodríguez‐Valera, Karyna Rosario, Lynn M. Schriml, Frederik Schulz, Grieg F. Steward, Matthew B. Sullivan, Shinichi Sunagawa, Curtis A. Suttle, Ben Temperton, Susannah G. Tringe, Rebecca Vega Thurber, Nicole S. Webster, Katrine L Whiteson, Steven W. Wilhelm, K. Eric Wommack, Tanja Woyke, Kelly Wrighton, Pelin Yilmaz, Takashi Yoshida, Mark Young, Natalya Yutin, Lisa Zeigler Allen, Nikos C. Kyrpides, Emiley A. Eloe‐Fadrosh

Bibliographic record

VenueNature Biotechnology · 2018
Typearticle
Languageen
FieldEnvironmental Science
TopicBacteriophages and microbial interactions
Canadian institutionsUniversity of British ColumbiaFisheries and Oceans CanadaUniversity of Guelph
FundersLawrence Berkeley National LaboratoryU.S. National Library of MedicineNational Institute of Allergy and Infectious DiseasesNational Institute of General Medical SciencesNational Institute of Diabetes and Digestive and Kidney DiseasesBiotechnology and Biological Sciences Research CouncilNational Institutes of HealthKU LeuvenLaboratory Directed Research and DevelopmentNederlandse Organisatie voor Wetenschappelijk OnderzoekBattelleAgence Nationale de la RechercheCenter for Dark Energy Biosphere InvestigationsSight Research UKVanderbilt UniversityNatural Environment Research CouncilEuropean Molecular Biology LaboratoryEunice Kennedy Shriver National Institute of Child Health and Human DevelopmentCairo UniversityU.S. Department of EnergyGordon and Betty Moore FoundationSimons FoundationNational Science Foundation
KeywordsGenomeBiologyVirusVirologyComputational biologyGeneticsGene

Abstract

fetched live from OpenAlex

We present an extension of the Minimum Information about any (x) Sequence (MIxS) standard for reporting sequences of uncultivated virus genomes. Minimum Information about an Uncultivated Virus Genome (MIUViG) standards were developed within the Genomic Standards Consortium framework and include virus origin, genome quality, genome annotation, taxonomic classification, biogeographic distribution and in silico host prediction. Community-wide adoption of MIUViG standards, which complement the Minimum Information about a Single Amplified Genome (MISAG) and Metagenome-Assembled Genome (MIMAG) standards for uncultivated bacteria and archaea, will improve the reporting of uncultivated virus genomes in public databases. In turn, this should enable more robust comparative studies and a systematic exploration of the global virosphere.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.006
metaresearch head score (Gemma)0.019
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.006
Threshold uncertainty score0.030

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0060.019
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0050.003
Science and technology studies0.0010.001
Scholarly communication0.0020.003
Open science0.0020.002
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0050.003

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.004
GPT teacher head0.235
Teacher spread0.231 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations790
Published2018
Admission routes1
Has abstractyes

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