MétaCan
Menu
Back to cohort
Record W2963978412 · doi:10.1016/j.omto.2019.07.003

Coxsackievirus Type B3 Is a Potent Oncolytic Virus against KRAS-Mutant Lung Adenocarcinoma

2019· article· en· W2963978412 on OpenAlexafffund
Haoyu Deng, Huitao Liu, Tanya de Silva, Yuan Chao Xue, Yasir Mohamud, Chen Seng Ng, Junyan Qu, Jingchun Zhang, William Jia, William W. Lockwood, Honglin Luo

Bibliographic record

VenueMolecular Therapy — Oncolytics · 2019
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicVirus-based gene therapy research
Canadian institutionsOccupational Cancer Research CentreSt. Paul's HospitalUniversity of British Columbia
FundersNatural Sciences and Engineering Research Council of CanadaMichael Smith Health Research BCTerry Fox Research InstituteUniversity of British ColumbiaCanadian Lung AssociationBC Cancer FoundationVancouver Coastal Health Research InstituteBritish Columbia Lung AssociationCanadian Institutes of Health ResearchMitacsInternational Association for the Study of Lung Cancer
KeywordsOncolytic virusKRASVirologyAdenocarcinomaCoxsackievirusMutantCancer researchVirusBiologyMutationMedicineEnterovirusInternal medicineCancerGeneticsGene

Abstract

fetched live from OpenAlex

lung adenocarcinoma.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.048
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0000.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.296
Teacher spread0.279 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations47
Published2019
Admission routes2
Has abstractyes

Explore more

Same venueMolecular Therapy — OncolyticsSame topicVirus-based gene therapy researchFrench-language works237,207