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Record W2967929375 · doi:10.1101/734137

What difference do retractions make? An estimate of the epistemic impact of retractions on recent meta-analyses

2019· preprint· en· W2967929375 on OpenAlexaff
Daniele Fanelli, David Moher

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2019
Typepreprint
Languageen
FieldSocial Sciences
TopicAcademic integrity and plagiarism
Canadian institutionsOttawa Public HealthOttawa HospitalUniversity of Ottawa
Fundersnot available
KeywordsSample size determinationMeta-analysisPublication biasNull hypothesisStatisticsPsychologyEconometricsEpistemologyConfidence intervalMathematicsPhilosophyMedicine

Abstract

fetched live from OpenAlex

ABSTRACT Every year, several hundred publications are retracted due to fabrication and falsification of data or plagiarism and other breeches of research integrity and ethics. Despite considerable research on this phenomenon, the extent to which a retraction requires revising previous scientific estimates and beliefs – which we define as the epistemic impact - is unknown. We collected a representative sample of recently retracted studies that had been included in recent meta-analyses, and compared the summary effect size of these meta analyses with and without the refracted studies. On average, the retractions had occurred about six years prior to the publication of the corresponding meta-analyses. Our results suggest that retractions have varying impacts depending on their causes. In particular, removing from an analysis a study retracted because of issues with data, methods or results, led to a statistically significant reduction of the estimated effect size. Assuming that the results of these retracted studies are completely false, then the meta-analyses that had included them had overestimated the summary effect sizes by, averaging across effect size metrics, 30% (median, 13%). However, retractions due to plagiarism or other issues not related to data, methods or results had no impact on the conclusions of meta-analyses. Since retractions due to plagiarism or other non-data related issues typically constitute over 75% of total retractions, our results suggest that the epistemic impact of most retractions is likely to be null. However, our results also suggest that retractions due to issues with data, methods or results should be accompanied by a revision of relevant meta-analyses, and by extension a downwards revision of prior scientific beliefs.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Direct model labels (unvalidated)

Per-model category and study-design labels from the labeling rounds. They are machine output, unvalidated, and the disagreement between models ships as data. No study design here is MEDLINE-validated yet.

Model armCategoriesStudy designConfidence
gemmaMetaresearchResearch integrity
Domain: Evaluation · Genre: Empirical
About the Canadian research system: no · About a Canadian topic: no
Observationallow
gptMetaresearchResearch integrity
Domain: Evaluation · Genre: Empirical
About the Canadian research system: no · About a Canadian topic: no
Other designlow
models splitAgreement compares identical category sets and study designs across arms.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Research integrity
Consensus categoriesResearch integrity
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.735
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.001
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0020.004
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.109
GPT teacher head0.377
Teacher spread0.268 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Labeled directly by 2 models reading the full record.

MetaresearchResearch integrity

The models disagree on parts of this classification; every voice is preserved in the section at the end of the page.

Study designObservational · Other design
DomainEvaluation
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations11
Published2019
Admission routes1
Has abstractyes

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