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Record W2977833465 · doi:10.1038/s41588-019-0504-x

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

2019· article· en· W2977833465 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueNature Genetics · 2019
Typearticle
Languageen
FieldMedicine
TopicGout, Hyperuricemia, Uric Acid
Canadian institutionsMedpharmgene (Canada)Centre Hospitalier de l’Université de Montréal
FundersNational Institute of Diabetes and Digestive and Kidney DiseasesNational Heart, Lung, and Blood InstituteNational Institute of Arthritis and Musculoskeletal and Skin DiseasesMedical Research CouncilBritish Heart FoundationAlbert-Ludwigs-Universität FreiburgNational Human Genome Research InstituteWellcome TrustNederlandse Organisatie voor Wetenschappelijk OnderzoekAgence Nationale de la RechercheGlaxoSmithKlineDeutsche ForschungsgemeinschaftEunice Kennedy Shriver National Institute of Child Health and Human DevelopmentEuropean Regional Development FundEuropean CommissionNational Institute of General Medical SciencesNational Institute for Health and Care ResearchAmerican Heart AssociationNational Institutes of HealthU.S. Department of Health and Human Services
KeywordsBiologyGenome-wide association studyExpression quantitative trait lociGeneticsPleiotropyQuantitative trait locusGeneGenetic associationSingle-nucleotide polymorphismPhenotypeGenotype

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.806
Threshold uncertainty score0.997

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.262
Teacher spread0.245 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it