MétaCan
Menu
Back to cohort

996 Disease Characteristics of Acute Hepatic Porphyria Patients: ENVISION, a Phase 3 Global, Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial

2019· article· en· W2979400106 on OpenAlexaff
Karl E. Anderson, Manisha Balwani, Eliane Sardh, Laurent Gouya, David C. Rees, Penelope E. Stein, Ulrich Stölzel, Paula Aguilera, D. Montgomery Bissell, Herbert L. Bonkovsky, Sioḃán Keel, Charles Parker, John D. Phillips, Samuel Silver, Jerzy Windyga, Delia D’Avola, Gayle Ross, Peter Stewart, Bruce Ritchie, Jeeyoung Oh, Pauline Harper, Jiaan‐Der Wang, Janneke G. Langendonk, Aneta Ivanova, Yutaka Horie, Elisabeth I. Minder, Daphne Vassiliou, Ilja Kubisch, Encarna Guillén‐Navarro, David Coman, Bruce Wang, Hung‐Chou Kuo, Sushama Scalera, Craig Penz, Zoe Hua, Amy Simon, John J. Ko, Paolo Ventura

Bibliographic record

VenueThe American Journal of Gastroenterology · 2019
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicPorphyrin Metabolism and Disorders
Canadian institutionsUniversity of Alberta HospitalAlberta Hospital Edmonton
Fundersnot available
KeywordsMedicineInternal medicineKidney diseasePlaceboPopulationChronic liver diseaseLiver diseaseAdverse effectMulticenter trialRandomized controlled trialGastroenterologySurgeryCirrhosisPathologyMulticenter study

Abstract

fetched live from OpenAlex

OpenAlex records an abstract for this work, but it could not be fetched just now.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Randomized trial · Consensus signal: Randomized trial
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.012
Threshold uncertainty score0.737

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.005
GPT teacher head0.266
Teacher spread0.261 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designRandomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2019
Admission routes1
Has abstractyes

Explore more

Same venueThe American Journal of GastroenterologySame topicPorphyrin Metabolism and DisordersFrench-language works237,207