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Record W2995524930 · doi:10.1016/j.jpain.2019.12.003

Improving Study Conduct and Data Quality in Clinical Trials of Chronic Pain Treatments: IMMPACT Recommendations

2019· article· en· W2995524930 on OpenAlexafffund
Jennifer S. Gewandter, Robert H. Dworkin, Dennis C. Turk, Eric Devine, David Hewitt, Mark P. Jensen, Nathaniel P. Katz, Amy A. Kirkwood, Richard Malamut, John D. Markman, Bernard Vrijens, Laurie B. Burke, James N. Campbell, Daniel B. Carr, Philip G. Conaghan, Penney Cowan, Mittie K. Doyle, Robert R. Edwards, Scott Evans, John T. Farrar, Roy Freeman, Ian Gilron, D. Juge, Robert D. Kerns, Ernest A. Kopecky, Michael P. McDermott, Gwendolyn Niebler, Kushang V. Patel, Richard Rauck, Andrew S.C. Rice, Michael C. Rowbotham, Nelson E. Sessler, Lee S. Simon, Neil Singla, Vladimir Skljarevski, Tina Tockarshewsky, Geertrui F. Vanhove, Ajay D. Wasan, James Witter

Bibliographic record

VenueJournal of Pain · 2019
Typearticle
Languageen
FieldMedicine
TopicOpioid Use Disorder Treatment
Canadian institutionsQueen's University
FundersNational Institute on Drug AbuseNational Institute on Alcohol Abuse and AlcoholismCanadian Institutes of Health ResearchJohnson and JohnsonU.S. Food and Drug AdministrationNational Institutes of HealthNational Institute for Health and Care ResearchCancer Research UKAmerican Society of AnesthesiologistsQueen's UniversityPTC TherapeuticsNew York State Stem Cell ScienceAstellas Pharma USAmerican College of PhysiciansSchool of Medicine, Duke UniversityBiogenPfizerNational Academies of Sciences, Engineering, and MedicineInternational Association for the Study of PainInternational Fibrodysplasia Ossificans Progressiva AssociationLeeds Biomedical Research CentreEli Lilly and CompanyAstraZenecaCidara TherapeuticsCure SMANovartis Pharmaceuticals CorporationSpinal Muscular Atrophy FoundationBoston UniversityAmerican Pain SocietyU.S. Department of Veterans AffairsPatient-Centered Outcomes Research InstituteNational Multiple Sclerosis Society
KeywordsClinical trialMedicineQuality (philosophy)Data collectionMedical physicsPatient recruitmentData qualityClinical researchAssay sensitivityAlternative medicinePhysical therapyMetric (unit)BusinessPathologyMarketing

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.061
metaresearch head score (Gemma)0.011
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesMetaresearch
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.202
Threshold uncertainty score0.997

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0610.011
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.293
GPT teacher head0.541
Teacher spread0.247 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations58
Published2019
Admission routes2
Has abstractno

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