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New Approaches to SCLC Therapy: From the Laboratory to the Clinic

2020· review· en· 176 citations· W3003747453 on OpenAlex· 10.1016/j.jtho.2020.01.016

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.

Full frame distilled prediction

Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

Candidate categories
Research integrity
Consensus categories
none
Domain
Candidate signal: noneConsensus signal: none
Study design
Candidate signal: Not applicableConsensus signal: none
Genre
Candidate signal: ReviewConsensus signal: Review
Teacher disagreement score
0.709
Threshold uncertainty score
1.000
Validation status
machine_predicted_unvalidated · codex-gemma-dda1882f352a

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0030.001
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.002
Insufficient payload (model declined to judge)0.0000.001

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.364
GPT teacher head0.552
Teacher spread
0.189 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Journal of Thoracic Oncology
Topic
Lung Cancer Research Studies
Field
Medicine
Canadian institutions
Princess Margaret Cancer Centre
Funders
Janssen PharmaceuticalsNational Cancer InstituteNational Health and Medical Research CouncilDaiichi Sankyo EuropeAgios PharmaceuticalsKarolinska InstitutetTakeda OncologyEMD SeronoIpsenPharmaMarAstellas PharmaMerckKyowa Hakko KirinDaiichi-SankyoSyndax PharmaceuticalsCancer Research UKAstraZenecaInternational Association for the Study of Lung CancerGenentechANGLEBayer FundMeso Scale DiagnosticsAstex PharmaceuticalsTG TherapeuticsAeglea BioTherapeuticsPfizer PharmaceuticalsMarshfield Clinic Research FoundationMemorial Sloan-Kettering Cancer CenterMerck KGaANational Institutes of HealthRegeneron PharmaceuticalsVictorian Cancer AgencyIncyteMedical Research CouncilUniversity of Texas Southwestern Medical CenterAbbVieCelgeneNovartisFoundation MedicineGlaxoSmithKlineEli Lilly and CompanyBristol-Myers SquibbG1 TherapeuticsLung Cancer Research FoundationCold Spring Harbor LaboratoryRocheAstellas Pharma USAmgenAriad PharmaceuticalsBoehringer IngelheimPfizer
Keywords
MedicineIntensive care medicineLung cancerClinical trialImmunotherapyDiseaseOncologyCancerInternal medicine
Has abstract in OpenAlex
no