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Record W3004901913 · doi:10.1371/journal.pbio.3000597

Selective sweeps on novel and introgressed variation shape mimicry loci in a butterfly adaptive radiation

2020· article· en· W3004901913 on OpenAlexaff
Markus Moest, Steven M. Van Belleghem, Jennifer James, Camilo Salazar, Simon H. Martin, Sarah L. Barker, Gilson R. P. Moreira, Claire Mérot, Mathieu Joron, Nicola J. Nadeau, Florian M. Steiner, Chris D. Jiggins

Bibliographic record

VenuePLoS Biology · 2020
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetic diversity and population structure
Canadian institutionsUniversité Laval
FundersFP7 Ideas: European Research CouncilScience and Technology Facilities CouncilExploratory Research for Advanced TechnologyNatural Environment Research CouncilEngineering and Physical Sciences Research CouncilMedical Research CouncilDirectorate for Biological SciencesDell EMCUniversidad del RosarioIsaac Newton TrustSchweizerischer Nationalfonds zur Förderung der Wissenschaftlichen ForschungBiotechnology and Biological Sciences Research CouncilAustrian Science FundCHIST-ERAAgence Nationale de la RechercheNational Science FoundationUniversity of CambridgeSight Research UKConselho Nacional de Desenvolvimento Científico e TecnológicoDepartamento Administrativo de Ciencia, Tecnología e Innovación (COLCIENCIAS)
KeywordsBiologyMimicryButterflyEvolutionary biologyGeneticsAdaptation (eye)Variation (astronomy)Genetic variationAdaptive radiationComputational biologyZoologyGenePhylogeneticsEcology

Abstract

fetched live from OpenAlex

Natural selection leaves distinct signatures in the genome that can reveal the targets and history of adaptive evolution. By analysing high-coverage genome sequence data from 4 major colour pattern loci sampled from nearly 600 individuals in 53 populations, we show pervasive selection on wing patterns in the Heliconius adaptive radiation. The strongest signatures correspond to loci with the greatest phenotypic effects, consistent with visual selection by predators, and are found in colour patterns with geographically restricted distributions. These recent sweeps are similar between co-mimics and indicate colour pattern turn-over events despite strong stabilising selection. Using simulations, we compare sweep signatures expected under classic hard sweeps with those resulting from adaptive introgression, an important aspect of mimicry evolution in Heliconius butterflies. Simulated recipient populations show a distinct 'volcano' pattern with peaks of increased genetic diversity around the selected target, characteristic of sweeps of introgressed variation and consistent with diversity patterns found in some populations. Our genomic data reveal a surprisingly dynamic history of colour pattern selection and co-evolution in this adaptive radiation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.003

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.226
Teacher spread0.205 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations87
Published2020
Admission routes1
Has abstractyes

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