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Record W3041857881 · doi:10.1111/jcmm.15483

Ageing‐associated increase in SGLT2 disrupts mitochondrial/sarcoplasmic reticulum Ca<sup>2+</sup> homeostasis and promotes cardiac dysfunction

2020· article· en· W3041857881 on OpenAlexafffund
Yusuf Olğar, Erkan Tuncay, Sinan Değirmenci, Deniz Billur, Rimpy Dhingra, Lorrie A. Kirshenbaum, Belma Turan

Bibliographic record

VenueJournal of Cellular and Molecular Medicine · 2020
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicMitochondrial Function and Pathology
Canadian institutionsUniversity of ManitobaSt. Boniface Hospital
FundersCanadian Institutes of Health ResearchTürkiye Bilimsel ve Teknolojik Araştırma KurumuHealth Research
KeywordsHomeostasisPhospholambanContractilityMitochondrionInternal medicineEndocrinologyAgeingBiologyCell biologyReactive oxygen speciesSodium-calcium exchangerGlucose homeostasisCardiac function curveEndoplasmic reticulumCalciumMedicineHeart failureInsulin resistanceInsulin

Abstract

fetched live from OpenAlex

OpenAlex records an abstract for this work, but it could not be fetched just now.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.153
Threshold uncertainty score0.822

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.222
Teacher spread0.215 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations45
Published2020
Admission routes2
Has abstractyes

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