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Record W3123440733 · doi:10.1186/s12947-021-00238-1

A multicentric quality-control study of exercise Doppler echocardiography of the right heart and the pulmonary circulation. The RIGHT Heart International NETwork (RIGHT-NET)

2021· article· en· W3123440733 on OpenAlexaff
Francesco Ferrara, Luna Gargani, Carla Contaldi, Gergely Ágoston, Paola Argiento, William F. Armstrong, Francesco Bandera, Filippo Cademartiri, Rodolfo Citro, Antonio Cittadini, Rosangela Cocchia, Michele D’Alto, Antonello D’Andrea, Philipp Douschan, Stefano Ghio, Ekkehard Grünig, Marco Guazzi, Stefania Guida, Jarosław D. Kasprzak, Theodore J. Kolias, Giuseppe Limongelli, Alberto M. Marra, Matteo Mazzola, Ciro Mauro, Antonella Moreo, Francesco Pieri, Lorenza Pratali, Nicola Riccardo Pugliese, Mauro Raciti, Brigida Ranieri, Lawrence Rudski, Rajan Saggar, Andrea Salzano, Walter Serra, Anna Agnese Stanziola, Mani A. Vannan, Damien Voilliot, Olga Vriz, Karina Wierzbowska‐Drabik, Robert Naeije, Eduardo Bossone

Bibliographic record

VenueCardiovascular Ultrasound · 2021
Typearticle
Languageen
FieldMedicine
TopicCardiovascular Function and Risk Factors
Canadian institutionsMcGill UniversityJewish General Hospital
FundersUniversitätsklinikum HeidelbergSzegedi TudományegyetemUniversitatea de Medicină, Farmacie, Științe și Tehnologie din Târgu MureșBaker Heart and Diabetes InstituteMedizinische Universität GrazUniversità degli Studi di PadovaUniversità di PisaUniwersytet ŁódzkiUniversità degli Studi di Napoli Federico IIImperial College LondonKing Faisal Specialist Hospital and Research CentreVrije Universiteit BrusselLunds UniversitetKarl-Franzens-Universität GrazSkånes universitetssjukhusUniversità degli Studi di Milano
KeywordsMedicineCardiologyInternal medicineVentricular outflow tractEjection fractionDoppler echocardiographyDiastoleIntraclass correlationHeart failureBlood pressure

Abstract

fetched live from OpenAlex

PURPOSE: This study was a quality-control study of resting and exercise Doppler echocardiography (EDE) variables measured by 19 echocardiography laboratories with proven experience participating in the RIGHT Heart International NETwork. METHODS: All participating investigators reported the requested variables from ten randomly selected exercise stress tests. Intraclass correlation coefficients (ICC) were calculated to evaluate the inter-observer agreement with the core laboratory. Inter-observer variability of resting and peak exercise tricuspid regurgitation velocity (TRV), right ventricular outflow tract acceleration time (RVOT Act), tricuspid annular plane systolic excursion (TAPSE), tissue Doppler tricuspid lateral annular systolic velocity (S'), right ventricular fractional area change (RV FAC), left ventricular outflow tract velocity time integral (LVOT VTI), mitral inflow pulsed wave Doppler velocity (E), diastolic mitral annular velocity by TDI (e') and left ventricular ejection fraction (LVEF) were measured. RESULTS: The accuracy of 19 investigators for all variables ranged from 99.7 to 100%. ICC was > 0.90 for all observers. Inter-observer variability for resting and exercise variables was for TRV = 3.8 to 2.4%, E = 5.7 to 8.3%, e' = 6 to 6.5%, RVOT Act = 9.7 to 12, LVOT VTI = 7.4 to 9.6%, S' = 2.9 to 2.9% and TAPSE = 5.3 to 8%. Moderate inter-observer variability was found for resting and peak exercise RV FAC (15 to 16%). LVEF revealed lower resting and peak exercise variability of 7.6 and 9%. CONCLUSIONS: When performed in expert centers EDE is a reproducible tool for the assessment of the right heart and the pulmonary circulation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.053
Threshold uncertainty score0.745

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.005
Bibliometrics0.0000.001
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.233
Teacher spread0.225 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations22
Published2021
Admission routes1
Has abstractyes

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