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Record W3135275361 · doi:10.1093/jamiaopen/ooab012

Evaluating the utility of synthetic COVID-19 case data

2021· article· en· W3135275361 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.
aboutThe title or abstract carries a Canadian signal from the geographic lexicon.

Bibliographic record

VenueJAMIA Open · 2021
Typearticle
Languageen
FieldComputer Science
TopicPrivacy-Preserving Technologies in Data
Canadian institutionsChildren's Hospital of Eastern OntarioUniversity of Ottawa
FundersNatural Sciences and Engineering Research Council of CanadaCompute Canada
KeywordsProxy (statistics)Confidence intervalSynthetic dataComputer scienceMissing dataData miningCoronavirus disease 2019 (COVID-19)Data setComorbidityStatisticsMedicineArtificial intelligenceMachine learningMathematicsInternal medicine

Abstract

fetched live from OpenAlex

BACKGROUND: Concerns about patient privacy have limited access to COVID-19 datasets. Data synthesis is one approach for making such data broadly available to the research community in a privacy protective manner. OBJECTIVES: Evaluate the utility of synthetic data by comparing analysis results between real and synthetic data. METHODS: A gradient boosted classification tree was built to predict death using Ontario's 90 514 COVID-19 case records linked with community comorbidity, demographic, and socioeconomic characteristics. Model accuracy and relationships were evaluated, as well as privacy risks. The same model was developed on a synthesized dataset and compared to one from the original data. RESULTS: The AUROC and AUPRC for the real data model were 0.945 [95% confidence interval (CI), 0.941-0.948] and 0.34 (95% CI, 0.313-0.368), respectively. The synthetic data model had AUROC and AUPRC of 0.94 (95% CI, 0.936-0.944) and 0.313 (95% CI, 0.286-0.342) with confidence interval overlap of 45.05% and 52.02% when compared with the real data. The most important predictors of death for the real and synthetic models were in descending order: age, days since January 1, 2020, type of exposure, and gender. The functional relationships were similar between the two data sets. Attribute disclosure risks were 0.0585, and membership disclosure risk was low. CONCLUSIONS: This synthetic dataset could be used as a proxy for the real dataset.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.117
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Open science
Consensus categoriesOpen science
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: none
Teacher disagreement score0.835
Threshold uncertainty score0.923

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0040.117
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0820.441
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.379
GPT teacher head0.474
Teacher spread0.095 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it