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Record W3146762921 · doi:10.1016/j.jtct.2021.03.029

National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: IIb. The 2020 Preemptive Therapy Working Group Report

2021· article· en· W3146762921 on OpenAlexaff
Joseph Pidala, Carrie L. Kitko, Stephanie J. Lee, Paul A. Carpenter, Geoff D.E. Cuvelier, Shernan G. Holtan, Mary E.D. Flowers, Corey Cutler, Madan Jagasia, Ted Gooley, Joycelynne Palmer, Tim R Randolph, John E. Levine, Francis Ayuk, Fiona L. Dignan, Hélène Schoemans, Eric R. Tkaczyk, Nosha Farhadfar, Ánita Lawitschka, Kirk R. Schultz, Paul J. Martin, Stefanie Sarantopoulos, Yoshihiro Inamoto, Gèrard Socié, Daniel Wolff, Bruce R. Blazar, Hildegard Greinix, Sophie Paczesny, Steven Z. Pavletic, Geoffrey R. Hill

Bibliographic record

VenueTransplantation and Cellular Therapy · 2021
Typearticle
Languageen
FieldMedicine
TopicHematopoietic Stem Cell Transplantation
Canadian institutionsUniversity of ManitobaBritish Columbia Children's HospitalCancerCare Manitoba
FundersPharmacyclicsUniversität HamburgMeiji Seika PharmaCompass TherapeuticsSyndax PharmaceuticalsCTI BiopharmaAlvin J. Siteman Cancer CenterJazz PharmaceuticalsNational Institutes of HealthRegeneron PharmaceuticalsOmeros CorporationAnthony NolanHuntsman Cancer InstituteTakeda Pharmaceuticals U.S.A.Massachusetts General HospitalUniversity of MinnesotaJanssen PharmaceuticalsMemorial Sloan-Kettering Cancer CenterUniversity at BuffaloAbbVieClinical Science Research and DevelopmentUniversidad de SevillaNational Cancer InstituteGilead SciencesDana-Farber Cancer InstituteRocheNovartisCelgeneBristol-Myers SquibbAstraZenecaCareDxIncytePfizerAmgenU.S. Department of Veterans Affairs
KeywordsMedicineGraft-versus-host diseaseIntensive care medicineClinical trialDiseaseHematopoietic stem cell transplantationHematopoietic cellPsychological interventionTransplantationMalignancyImmunologyInternal medicineHaematopoiesisStem cell

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.326
metaresearch head score (Gemma)0.388
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Other · Consensus signal: none
Teacher disagreement score0.326
Threshold uncertainty score0.831

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.3260.388
Meta-epidemiology (narrow)0.0030.004
Meta-epidemiology (broad)0.0090.011
Bibliometrics0.0070.010
Science and technology studies0.0050.006
Scholarly communication0.0130.005
Open science0.0160.013
Research integrity0.0240.026
Insufficient payload (model declined to judge)0.0100.010

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.287
GPT teacher head0.462
Teacher spread0.175 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations41
Published2021
Admission routes1
Has abstractno

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