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Record W3162211911 · doi:10.31234/osf.io/urgtn

Z-Curve 2.0: Estimating Replication Rates and Discovery Rates

2020· preprint· en· W3162211911 on OpenAlexaff
Frantis̆ek Bartos̆, Ulrich Schimmack

Bibliographic record

Venuenot available
Typepreprint
Languageen
FieldMathematics
TopicStatistical Methods in Clinical Trials
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsReplication (statistics)Confidence intervalFalse discovery rateSelection (genetic algorithm)StatisticsFalse positive paradoxMultiple comparisons problemComputer scienceRange (aeronautics)Extension (predicate logic)EconometricsMathematicsArtificial intelligenceBiologyEngineering

Abstract

fetched live from OpenAlex

Selection for statistical significance is a well-known factor that distorts the published literature and challenges the cumulative progress in science. Recent replication failures have fueled concerns that many published results are false-positives. Brunner and Schimmack (2020) developed z-curve, a method for estimating the expected replication rate (ERR) – the predicted success rate of exact replication studies based on the mean power after selection for significance. This article introduces an extension of this method, z-curve 2.0. The main extension is an estimate of the expected discovery rate (EDR) – the estimate of a proportion that the reported statistically significant results constitute from all conducted statistical tests. This information can be used to detect and quantify the amount of selection bias by comparing the EDR to the observed discovery rate (ODR; observed proportion of statistically significant results). In addition, we examined the performance of bootstrapped confidence intervals in simulation studies. Based on these results, we created robust confidence intervals with good coverage across a wide range of scenarios to provide information about the uncertainty in EDR and ERR estimates. We implemented the method in the zcurve R package (Bartoš & Schimmack, 2020).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.233
metaresearch head score (Gemma)0.644
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesMetaresearch
DomainCandidate signal: Reproducibility · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.767
Threshold uncertainty score0.946

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.2330.644
Meta-epidemiology (narrow)0.0040.005
Meta-epidemiology (broad)0.0050.009
Bibliometrics0.0110.011
Science and technology studies0.0020.005
Scholarly communication0.0090.007
Open science0.0070.009
Research integrity0.0050.008
Insufficient payload (model declined to judge)0.0360.014

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.657
GPT teacher head0.610
Teacher spread0.047 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; the direct Gemma label and the distilled Codex classifier agree on what is shown here.

Study designSimulation or modeling
DomainReproducibility
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations38
Published2020
Admission routes1
Has abstractyes

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Same topicStatistical Methods in Clinical TrialsFrench-language works237,207