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Record W3181270705 · doi:10.1038/s41379-021-00865-z

Interobserver variability in the assessment of stromal tumor-infiltrating lymphocytes (sTILs) in triple-negative invasive breast carcinoma influences the association with pathological complete response: the IVITA study

2021· article· en· W3181270705 on OpenAlexaff
Mieke Van Bockstal, Aline François, Serdar Altınay, Laurent Arnould, Maschenka Balkenhol, Glenn Broeckx, Octavio Burgués, Cécile Colpaert, Franceska Dedeurwaerdere, Benjamin F. Dessauvagie, Valérie Duwel, Giuseppe Floris, Stephen B. Fox, Clara Gerosa, Delfyne Hastir, Shabnam Jaffer, Eline Kurpershoek, Magali Lacroix‐Triki, Andoni Laka, Kathleen Lambein, Gaëtan MacGrogan, Caterina Marchiò, Sharon Nofech‐Mozes, Dieter Peeters, Alberto Ravarino, Emily Reisenbichler, Erika Resetkova, Souzan Sanati, Anne‐Marie Schelfhout, Vera Schelfhout, Abeer M. Shaaban, Renata Sinke, Claudia Stanciu‐Pop, Carolien H. M. van Deurzen, Koen Van de Vijver, Anne‐Sophie Van Rompuy, Anne Vincent‐Salomon, Hannah Y. Wen, Serena Wong, Caroline Bouzin, Christine Galant

Bibliographic record

VenueModern Pathology · 2021
Typearticle
Languageen
FieldMedicine
TopicCancer Immunotherapy and Biomarkers
Canadian institutionsUniversity of TorontoSunnybrook Health Science Centre
FundersCliniques Universitaires Saint-LucU.S. Department of Health and Human ServicesNational Cancer InstituteFondation contre le CancerStichting Tegen KankerFondation Saint Luc
KeywordsMedicineBiopsyPathologicalBreast cancerPathologyIntraclass correlationRenal cell carcinomaCancerInternal medicine

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.006
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.029
Threshold uncertainty score0.361

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0060.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.032
GPT teacher head0.303
Teacher spread0.271 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations61
Published2021
Admission routes1
Has abstractno

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