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Record W3203021509 · doi:10.1016/j.ocarto.2021.100215

The state of trial registrations in the field of Orthopaedics in years 2015–2020. A meta-epidemiological study

2021· review· en· W3203021509 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueOsteoarthritis and Cartilage Open · 2021
Typereview
Languageen
FieldDecision Sciences
TopicMeta-analysis and systematic reviews
Canadian institutionsWestern UniversityHand and Upper Limb ClinicSt. Joseph's HospitalUniversity of TorontoQueen's UniversityCanadian Institute for Military and Veteran Health Research
Fundersnot available
KeywordsMedicineRandomized controlled trialEpidemiologyPopulationMeta-analysisOrthopedic surgeryTrial registrationMEDLINEProspective cohort studySurgeryInternal medicineEnvironmental health

Abstract

fetched live from OpenAlex

Objective: To assess the extent and trends in registration of Orthopaedic randomized clinical trials (RCTs) between 2015 and 2020. Design: Epidemiological study. Primary publications of RCTs published in top Orthopaedic journals (ISI Journal Citation Reports 2019 rankings) between 2015 and 2020 were included in this meta-epidemiological study with no restrictions on patient population, intervention/control groups or outcome type. Independent reviewers in pairs were involved in RCT selection and data extraction. The proportion of RCTs published that were registered (prospectively or retrospectively) or not registered were reported using counts and percentages stratified by years for each journal. Results: A total of 474 primary RCTs were considered eligible. We identified 157 out of 474 RCTs (33% of RCTs across journals) that were reported to have been registered prospectively.The proportion of prospective RCT registrations had increased by 40% (10%-50%) between 2015 and 2020. On the other hand, the proportion of RCTs with no registrations were reduced by 29% (50%-21%) between 2015 and 2020. Conclusion: Prospective RCT registration in the past 5 years in the field of orthopaedic has increased, but 2/3 of published RCTs still failed to report prospective registration.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Direct model labels (unvalidated)

Per-model category and study-design labels from the labeling rounds. They are machine output, unvalidated, and the disagreement between models ships as data. No study design here is MEDLINE-validated yet.

Model armCategoriesStudy designConfidence
gemmaMetaresearchMeta-epidemiology (broad)Meta-epidemiology (narrow)
Domain: Reporting · Genre: Review
About the Canadian research system: no · About a Canadian topic: no
Systematic reviewhigh
gptMetaresearchMeta-epidemiology (broad)
Domain: Reporting · Genre: Empirical
About the Canadian research system: no · About a Canadian topic: no
Observationalmedium
models splitAgreement compares identical category sets and study designs across arms.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.153
metaresearch head score (Gemma)0.038
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesMetaresearch
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.987
Threshold uncertainty score0.970

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.1530.038
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0110.003
Bibliometrics0.0000.002
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0030.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.650
GPT teacher head0.563
Teacher spread0.087 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it