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Record W3208590696 · doi:10.1038/s41587-021-01058-4

Population genomic analysis of Aegilops tauschii identifies targets for bread wheat improvement

2021· article· en· W3208590696 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueNature Biotechnology · 2021
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicWheat and Barley Genetics and Pathology
Canadian institutionsUniversity of SaskatchewanUniversity of British Columbia
FundersDepartment of Plant Sciences, University of California, DavisAgricultural Research ServiceNational Institute of Food and AgricultureDirectorate for Biological SciencesSaskatchewan Wheat Development CommissionDeutsches Zentrum für integrative Biodiversitätsforschung Halle-Jena-LeipzigUniversität ZürichPunjab Agricultural UniversityKementerian Riset, Teknologi dan Pendidikan TinggiNanjing Agricultural UniversitySichuan Agricultural UniversityTel Aviv UniversityIlam UniversityUniversity of British ColumbiaInstituto Nacional de Investigación AgropecuariaAarhus UniversitetJohn Innes FoundationOeAD-GmbHChinese Academy of Agricultural SciencesInnovationsfondenU.S. Department of AgricultureSchweizerischer Nationalfonds zur Förderung der Wissenschaftlichen ForschungKing Saud UniversityLeibniz-GemeinschaftResearch Councils UKUniversity of California, DavisACT GovernmentNational Natural Science Foundation of ChinaNational Science FoundationUK Research and InnovationUniversity of MinnesotaKing Abdullah University of Science and TechnologyDepartment of Biotechnology, Ministry of Science and Technology, IndiaInternational Center for Agricultural Research in the Dry AreasEuropean CommissionUniversità di BolognaKansas Wheat CommissionBiotechnology and Biological Sciences Research CouncilJewish National FundFulbright AssociationMinistry of Agriculture - SaskatchewanASEAN-European Academic University NetworkUniversitas Gadjah MadaInstituto Nacional de Investigación y Tecnología Agraria y AlimentariaÖsterreichische Agentur für Internationale Mobilität und Kooperation in Bildung, Wissenschaft und ForschungConsejo Nacional de Ciencia y TecnologíaUniversität für Bodenkultur WienRoyal Society
KeywordsAegilops tauschiiBiologyAegilopsPopulationGeneticsBiotechnologyGeneGenomeMedicine

Abstract

fetched live from OpenAlex

Aegilops tauschii, the diploid wild progenitor of the D subgenome of bread wheat, is a reservoir of genetic diversity for improving bread wheat performance and environmental resilience. Here we sequenced 242 Ae. tauschii accessions and compared them to the wheat D subgenome to characterize genomic diversity. We found that a rare lineage of Ae. tauschii geographically restricted to present-day Georgia contributed to the wheat D subgenome in the independent hybridizations that gave rise to modern bread wheat. Through k-mer-based association mapping, we identified discrete genomic regions with candidate genes for disease and pest resistance and demonstrated their functional transfer into wheat by transgenesis and wide crossing, including the generation of a library of hexaploids incorporating diverse Ae. tauschii genomes. Exploiting the genomic diversity of the Ae. tauschii ancestral diploid genome permits rapid trait discovery and functional genetic validation in a hexaploid background amenable to breeding.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.188
Threshold uncertainty score0.607

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.233
Teacher spread0.224 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it