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Strengthening the reporting of observational studies in epidemiology using mendelian randomisation (STROBE-MR): explanation and elaboration

2021· article· en· 1,684 citations· W3210406414 on OpenAlex· 10.1136/bmj.n2233

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Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.
Canadian funderA Canadian agency funded it. The work may carry no Canadian affiliation at all.

Machine scores (provisional)

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Opus teacher head0.250
GPT teacher head0.435
Teacher spread
0.185 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

In observational epidemiology, mendelian randomisation (MR) studies provide an opportunity to study the causal association between an exposure and an outcome while reducing the risk of certain biases Little consensus exists around the reporting of MR studies, and the quality of reporting of these studies has been inconsistent; many MR study reports do not state or examine the various assumptions of MR and report insufficient details on the data sources STROBE-MR (strengthening the reporting of observational studies in epidemiology using mendelian randomisation), a checklist of 20 reporting items, has been developed for the communication of MR studies This article explains the rationale of these checklist items and provides examples of transparent reporting MR study authors, reviewers, and journal editors are encouraged to use STROBE-MR to improve the reporting of these studies on 18 July

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The record

Venue
BMJ
Topic
Genetic Associations and Epidemiology
Field
Biochemistry, Genetics and Molecular Biology
Canadian institutions
McGill UniversityJewish General Hospital
Funders
Department of Health and Social CareMedical Research CouncilZonMwNational Institutes of HealthSchweizerischer Nationalfonds zur Förderung der Wissenschaftlichen ForschungPublic Health AgencyNational Cancer InstituteUniversity of BristolJewish General HospitalKing's College LondonPublic Health Agency of CanadaNational Institute for Health and Care ResearchUniversity Hospitals Bristol NHS Foundation TrustNIHR Bristol Biomedical Research CentreCanadian Institutes of Health ResearchNational Science FoundationCompute CanadaNorges ForskningsrådWorld Health OrganizationWellcome TrustCancer Research UKNederlandse Organisatie voor Wetenschappelijk OnderzoekEconomic and Social Research CouncilEuropean Commission
Keywords
Strengthening the reporting of observational studies in epidemiologyObservational studyChecklistQuality (philosophy)Meaning (existential)MedicineGlossaryElaborationMEDLINEEpidemiologyPsychologyMedical educationPathologyLinguisticsPolitical scienceCognitive psychology
Has abstract in OpenAlex
yes