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Record W4206272014 · doi:10.1101/2022.01.13.476155

Transatlantic spread of highly pathogenic avian influenza H5N1 by wild birds from Europe to North America in 2021

2022· preprint· en· W4206272014 on OpenAlexafffundabout
Valentina Caliendo, Nicola S. Lewis, Anne Pohlmann, Stephen R. Baillie, Ashley C. Banyard, Martin Beer, Ian H. Brown, Ron A. M. Fouchier, Rowena Hansen, Thomas K. Lameris, Andrew S. Lang, Sonja Laurendeau, Oliver Lung, Gregory J. Robertson, Henk P. van der Jeugd, Tamiru N. Alkie, Kasper Thorup, Mariëlle L. van Toor, Jonas Waldenström, Carmencita Yason, Thijs Kuiken, Yohannes Berhane

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2022
Typepreprint
Languageen
FieldMedicine
TopicInfluenza Virus Research Studies
Canadian institutionsEnvironment and Climate Change CanadaUniversity of Prince Edward IslandCanadian Food Inspection AgencyMemorial University of Newfoundland
FundersNational Institute of Allergy and Infectious DiseasesHorizon 2020 Framework ProgrammeBundesministerium für Bildung und ForschungU.S. Department of Health and Human ServicesNational Institutes of HealthDepartment for Environment, Food and Rural Affairs, UK GovernmentEnvironment and Climate Change Canada
KeywordsInfluenza A virus subtype H5N1Highly pathogenicWaterfowlGooseGeographyBird migrationOutbreakAvian influenza virusBiologyWildlifeVirologyZoologyVirusEcologyHabitat

Abstract

fetched live from OpenAlex

Abstract Highly pathogenic avian influenza (HPAI) viruses of the A/Goose/Guangdong/1/1996 lineage (GsGd), which threaten the health of poultry, wildlife and humans, are spreading across Asia, Europe and Africa, but are currently absent from Oceania and the Americas. In December 2021, H5N1 HPAI viruses were detected in poultry and a free-living gull in St. John’s, Newfoundland and Labrador, Canada. Phylogenetic analysis showed that these viruses were most closely related to HPAI GsGd viruses circulating in northwestern Europe in spring 2021. Analysis of wild bird migration suggested that these viruses may have been carried across the Atlantic via Iceland, Greenland/Arctic or pelagic routes. The here documented incursion of HPAI GsGd viruses into North America raises concern for further virus spread across the Americas by wild bird migration. One-Sentence Summary Detection of H5N1 highly pathogenic avian influenza in Canada raises concern for spread in the Americas by migratory birds.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.678
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0020.000
Bibliometrics0.0010.003
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0000.002
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.027
GPT teacher head0.278
Teacher spread0.251 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations30
Published2022
Admission routes3
Has abstractyes

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