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Peer Review #2 of "Reference values for bone density and bone mineral content from 5 to 80 years old in a province of Chile (v0.1)"

2022· peer-review· en· W4220984482 on OpenAlexfundno aff
Marco Cossio‐Bolaños, Rubén Vidal-Espinoza, Marco Cossio‐Bolaños, Luís Felipe, Castelli Correia De Campos, Cynthia Lee Andruske, Camilo Urra-Albornoz, Fernando Alvear-Vasquez, Rossana Campos, Felipe Castelli, Correia De Campos, Rossana Gómez‐Campos

Bibliographic record

Venuenot available
Typepeer-review
Languageen
FieldMedicine
TopicBone health and osteoporosis research
Canadian institutionsnot available
FundersUniversity of Saskatchewan
KeywordsBone mineral contentBone mineralMineralMedicineBiologyInternal medicineOsteoporosisEcology

Abstract

fetched live from OpenAlex

Background: The assessment of bone health throughout the life cycle is essential to determine fracture risk.The objectives of the work were a) compare bone mineral density and content with international references from the United States, b) determine maximum bone mass, c) propose references for bone health measurements from age 5 to 80 years old.Methods: Research was carried out on 5,416 subjects.Weight and height were measured.Body Mass Index (BMI) was calculated.The total body was scanned using dual energy X-ray absorptiometry (DXA).Information was extracted from the bone health measures [Bone mineral density (BMD) and bone mineral content (BMC)] for both sexes, according to pediatric and adult software.Results and Discussion: Differences were identified between the mean values of Chilean and American men for BMD (~0.03 to 0.11 g/cm2) and BMC (~0.15 to 0.46 g).The Chilean females showed average values for BMD similar to the US references (~ -0.01 to 0.02 g/cm2).At the same time, they were relatively higher for BMC (~ 0.07 to 0.33g).The cubic polynomial regression model reflected a relationship between BMD and BMC with chronological age in both sexes.For males, R 2 was higher (R 2 = 0.72 and 0.75) than for females (R 2 = 0.59 and 0.66).The estimate of maximum Bone Mass (MBM) for males emerged at 30 years old (1.45±0.18g/cm 2 of BMD and 3.57±0.60g of BMC) and for females at age 28 (1.22±0.13g/cm 2 of BMD and 2.57±0.44g of BMC).The LMS technique was used to generate smoothed percentiles for BMD and BMC by age and sex.Results showed that maximum bone mass occurred in PeerJ reviewing

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.013
metaresearch head score (Gemma)0.076
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: Evaluation · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Other · Consensus signal: none
Teacher disagreement score0.987
Threshold uncertainty score0.963

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0130.076
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0020.002
Bibliometrics0.0070.004
Science and technology studies0.0040.001
Scholarly communication0.0100.004
Open science0.0040.005
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.3250.215

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.118
GPT teacher head0.388
Teacher spread0.271 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designNot applicable
DomainEvaluation
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2022
Admission routes1
Has abstractyes

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