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Record W4245416002 · doi:10.7287/peerj.preprints.832

Assessing the reproducibility of discriminant function analyses

2015· preprint· en· W4245416002 on OpenAlexaff
Rose L. Andrew, Arianne Albert, Sébastien Renaut, Diana J. Rennison, Dan G. Bock, Tim Vines

Bibliographic record

Venuenot available
Typepreprint
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicMetabolomics and Mass Spectrometry Studies
Canadian institutionsGenome British ColumbiaUniversité de MontréalB.C. Women's Hospital & Health CentreWomen's Health Research InstituteUniversity of British Columbia
Fundersnot available
KeywordsComputer scienceDiscriminant function analysisFunction (biology)StatisticsVariance (accounting)Field (mathematics)MetadataData miningDiscriminantData scienceInformation retrievalArtificial intelligenceMachine learningMathematicsBiologyWorld Wide Web

Abstract

fetched live from OpenAlex

Data are the foundation of empirical research, yet all too often the datasets underlying published papers are unavailable, incorrect, or poorly curated. This is a serious issue, because future researchers are then unable to validate published results or reuse data to explore new ideas and hypotheses. While data files may be securely stored and accessible, they must also be accompanied by accurate labels and identifiers. To assess how often problems with metadata or data curation affect the reproducibility of published results, we attempted to reproduce Discriminant Function Analyses (DFAs) from the field of organismal biology. DFA is a commonly used statistical analysis that has changed little since its inception almost eight decades ago, and therefore provides an excellent case study to test reproducibility. Out of 100 papers we initially surveyed, fourteen were excluded because they did not present the common types of quantitative result from their DFA, used complex and unique data transformations, or gave insufficient details of their DFA. Of the remaining 86 datasets, there were 16 cases for which we were unable to confidently relate the dataset we received to the one used in the published analysis. The reasons ranged from incomprehensible or absent variable labels, the DFA being performed on an unspecified subset of the data, or incomplete data sets. We focused on reproducing three common summary statistics from DFAs: the percent variance explained, the percentage correctly assigned and the largest discriminant function coefficient. The reproducibility of the first two was high (20 of 25 and 43 of 59 datasets, respectively), whereas our success rate with the discriminant function coefficients was lower (15 of 36 datasets). When considering all three summary statistics, we were able to completely reproduce 46 (66%) of 70 datasets. While our results are encouraging, they highlight the fact that science still has some way to go before we have the carefully curated and reproducible research that the public expects.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.215
metaresearch head score (Gemma)0.518
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesMetaresearch
DomainCandidate signal: Reproducibility · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.785
Threshold uncertainty score0.968

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.2150.518
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0020.005
Bibliometrics0.0150.012
Science and technology studies0.0020.005
Scholarly communication0.0070.004
Open science0.0030.005
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0030.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.136
GPT teacher head0.407
Teacher spread0.271 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; the direct Gemma label and the distilled Codex classifier agree on what is shown here.

Study designSimulation or modeling
DomainReproducibility
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2015
Admission routes1
Has abstractyes

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