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Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

2022· review· en· 739 citations· W4280552086 on OpenAlex· 10.1038/s41588-022-01058-3

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.
Canadian funderA Canadian agency funded it. The work may carry no Canadian affiliation at all.

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.068
GPT teacher head0.359
Teacher spread
0.290 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Nature Genetics
Topic
Genetic Associations and Epidemiology
Field
Biochemistry, Genetics and Molecular Biology
Canadian institutions
McGill UniversityImpactHamilton Health SciencesUniversity of TorontoMcMaster UniversityPopulation Health Research Institute
Funders
National Heart, Lung, and Blood InstituteNational Center for Advancing Translational SciencesMedical Research CouncilGenentechNational Cancer InstituteServierShionogiNovo Nordisk FondenNovo NordiskVertex PharmaceuticalsSteno Diabetes Center CopenhagenWellcome TrustNational Institutes of HealthRegeneron PharmaceuticalsRespicardiaHarvard UniversityU.S. Department of Health and Human ServicesKowa CompanyNational Institute of Diabetes and Digestive and Kidney DiseasesSanofiNational Institute on AgingNational Institute for Health and Care ResearchMassachusetts General HospitalGlaxoSmithKlineGuangdong Provincial People's HospitalEli Lilly and CompanyBristol-Myers SquibbAstraZenecaAmgenPfizerSteno Diabetes Center AarhusMcMaster UniversityYale University
Keywords
BiologyType 2 diabetesTranslation (biology)GeneticsComputational biologyEvolutionary biologyType (biology)Genetic genealogyDiabetes mellitusDemographyPopulationGeneSociologyEndocrinologyEcology
Has abstract in OpenAlex
no