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Record W4283798787 · doi:10.1053/j.gastro.2022.06.068

CORE-IBD: A Multidisciplinary International Consensus Initiative to Develop a Core Outcome Set for Randomized Controlled Trials in Inflammatory Bowel Disease

2022· article· en· W4283798787 on OpenAlexafffund
Christopher Ma, Jurij Hanžel, Remo Panaccione, William J. Sandborn, Geert D’Haens, Vineet Ahuja, Raja Atreya, Çharles N. Bernstein, Peter Bossuyt, Brian Bressler, Robert V. Bryant, Benjamin L. Cohen, Jean‐Frédéric Colombel, Silvio Danese, Axel Dignaß, Marla C. Dubinsky, Phillip Fleshner, Richard B. Gearry, Stephen B. Hanauer, Ailsa Hart, Paulo Gustavo Kotze, Torsten Kucharzik, Péter L. Lakatos, Rupert W. Leong, Fernando Magro, Julián Panés, Laurent Peyrin‐Biroulet, Zhihua Ran, Miguel Regueiro, Siddharth Singh, Antonino Spinelli, A. Hillary Steinhart, Simon Travis, C. Janneke van der Woude, Bruce Yacyshyn, Takayuki Yamamoto, Matthieu Allez, Willem A. Bemelman, Amy L. Lightner, Édouard Louis, David T. Rubin, Ellen Scherl, Corey A. Siegel, Mark S. Silverberg, Séverine Vermeire, Claire E. Parker, Stefanie C. McFarlane, Leonardo Guizzetti, Michelle I. Smith, Niels Vande Casteele, Brian G. Feagan, Vipul Jairath

Bibliographic record

VenueGastroenterology · 2022
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicInflammatory Bowel Disease
Canadian institutionsWestern UniversityUniversity of TorontoMount Sinai HospitalSt. Paul's HospitalUniversity of CalgaryMcGill UniversityUniversity of British ColumbiaUniversity of Manitoba
FundersCanadian Institutes of Health ResearchTakeda CanadaPfizer CanadaShireGenentechPrometheus BiosciencesBristol-Myers Squibb CanadaProtagonist TherapeuticsJanssen PharmaceuticalsGilead SciencesAbbVie CanadaSeres TherapeuticsJanssen CanadaAmgen CanadaSanofiRocheGlaxoSmithKlinePfizer
KeywordsMedicineCalprotectinRandomized controlled trialCrohn's diseaseUlcerative colitisInflammatory bowel diseaseClinical trialInternal medicineClinical endpointMultidisciplinary approachDelphi methodOutcomes researchPatient-reported outcomeDiseasePhysical therapyQuality of life (healthcare)Alternative medicinePathology

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.006
metaresearch head score (Gemma)0.011
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Meta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Randomized trial · Consensus signal: Randomized trial
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.061
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0060.011
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.063
GPT teacher head0.348
Teacher spread0.285 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designRandomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations79
Published2022
Admission routes2
Has abstractno

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