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Record W4285012613 · doi:10.1111/1471-0307.12890

Enzymatic bioactive peptides from sonicated whey proteins of camel milk: Impacts of nanopeptides on structural properties, antioxidant activity and inhibitory activity of alpha‐amylase and <scp>ACE</scp>

2022· article· en· W4285012613 on OpenAlexaff
Sana Gammoh, Muhammad H. Alu’datt, Mohammad N. Alhamad, Mohammad Alrosan, Belal Al‐Husein, Doa’a Al-u’datt, Sharifa Alkandari, Taha Rababah, Zaid Ammari, Borhan Albiss, Haya Alzoubi, Stan Kubow

Bibliographic record

VenueInternational Journal of Dairy Technology · 2022
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicProtein Hydrolysis and Bioactive Peptides
Canadian institutionsMcGill University
FundersJordan University of Science and Technology
KeywordsHydrolysateChemistryAntioxidantWhey proteinSonicationPepsinTrypsinChymotrypsinHydrolysisEnzymatic hydrolysisAmylaseFood scienceBiochemistryEnzymeChromatography

Abstract

fetched live from OpenAlex

This study was carried out to investigate the biological properties of bioactive peptides derived from digestive enzymatic hydrolysis for nanoscaled protein particles from camel whey proteins. The hydrolysates were tested for aromatic content, antioxidant activity, α‐amylase inhibitory and angiotensin‐converting enzyme (ACE) activities. The sonicated camel whey protein particles showed sizes less than 100 nm and were distributed in a 75% volume with a relatively stable −23.1 mV zeta potential value. Sonication enhanced the total aromatic ring content in the hydrolysates generated by combined trypsin and chymotrypsin treatment. A decrease in antioxidant activity was shown following trypsin and chymotrypsin hydrolysis that was inhibited by whey protein sonication. Pepsin hydrolysis improved aromatic content, ACE and α‐amylase inhibitory activities, and antioxidant activity. An increase in antioxidant activity of the pepsin‐derived hydrolysates was seen with sonicated whey proteins. Overall, the findings demonstrate the utility of the application of enzymatic hydrolysis and/or ultrasonication of camel whey proteins to enhance their antioxidant, anti‐hypertensive and anti‐diabetic properties.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.000
Threshold uncertainty score0.001

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.236
Teacher spread0.227 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations13
Published2022
Admission routes1
Has abstractyes

Explore more

Same venueInternational Journal of Dairy TechnologySame topicProtein Hydrolysis and Bioactive PeptidesFrench-language works237,207