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Record W4285105512 · doi:10.1504/ijma.2022.10047304

Automated real-time 3D visual servoing control of single cell surgery with application to microinjection processes

2022· article· en· W4285105512 on OpenAlexaff
Bo Yao, James K. Mills

Bibliographic record

VenueInternational Journal of Mechatronics and Automation · 2022
Typearticle
Languageen
FieldEngineering
TopicPiezoelectric Actuators and Control
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsPipetteMicroinjectionVisual servoingProcess (computing)AutomationComputer scienceComputer visionArtificial intelligenceEngineeringImage (mathematics)ChemistryBiologyCell biologyMechanical engineering

Abstract

fetched live from OpenAlex

Automating the cell surgery processes is a potential solution to eliminate human involvement and promote the development of cell surgery. Here, we propose a real-time 3D visual servocontrol system for single cell surgery with the experimental results of single cell injection of an embryo and analysis of experimental data. Real time 3D image processes are a necessary requirement since during cell surgery, when a micropipette contacts the embryo, the embryo is deformed, repositioning the internal components of the cell to be injected. An innovative 3D edge extraction algorithm is demonstrated for the real time 3D image processes. Visual servocontrol of the cell surgery process acquires the real-time target cell blastomere 3 dimensional position is used to maneuver the micropipette under real-time closed-loop feedback control. The automated embryo microinjection process is conducted using the proposed real-time 3D visual servocontrol system, which is proven to be a potential solution for microinjection automation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.001
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.002
GPT teacher head0.191
Teacher spread0.189 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2022
Admission routes1
Has abstractyes

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Same venueInternational Journal of Mechatronics and AutomationSame topicPiezoelectric Actuators and ControlFrench-language works237,207