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Record W4292253343 · doi:10.1016/j.ctrv.2022.102455

Retrospective observational studies in ultra-rare sarcomas: A consensus paper from the Connective Tissue Oncology Society (CTOS) community of experts on the minimum requirements for the evaluation of activity of systemic treatments

2022· review· en· W4292253343 on OpenAlexaff
Silvia Stacchiotti, Anna Maria Frezza, George D. Demetri, Jean‐Yves Blay, Jyoti Bajpai, Giacomo Giulio Baldi, Elizabeth H. Baldini, Robert S. Benjamin, Sylvie Bonvalot, Judith V.M.G. Bovée, Dario Callegaro, Paolo G. Casali, Sandra P. D’Angelo, Elizabeth J. Davis, Angelo Paolo Dei Tos, Elizabeth G. Demicco, Jayesh Desai, Palma Dileo, Mikael Eriksson, Hans Gelderblom, Suzanne George, Rebecca A. Gladdy, Mrinal M. Gounder, Abha A. Gupta, Rick L. M. Haas, Andrea Giráldez Hayes, Peter Hohenberger, Kevin B. Jones, Robin L. Jones, Bernd Kasper, Akira Kawai, David G. Kirsch, Eugenie S. Kleinerman, Axel Le Cesne, Roberta Maestro, Javier Martín‐Broto, Robert G. Maki, Aisha Miah, Emanuela Palmerini, Shreaskumar R. Patel, Chandrajit P. Raut, Albiruni R. Abdul Razak, Damon R. Reed, Piotr Rutkowski, Roberta Sanfilippo, Marta Sbaraglia, Inga‐Marie Schaefer, D. Strauß, Sandra J. Strauss, William D. Tap, David M. Thomas, Annalisa Trama, Jonathan C. Trent, Winette T.A. van der Graaf, Winan J. van Houdt, Margaret von Mehren, Breelyn A. Wilky, Christopher D.�M. Fletcher, Alessandro Gronchi, Rosalba Miceli, Andrew J. Wagner

Bibliographic record

VenueCancer Treatment Reviews · 2022
Typereview
Languageen
FieldMedicine
TopicSarcoma Diagnosis and Treatment
Canadian institutionsHospital for Sick ChildrenPrincess Margaret Cancer CentreUniversity of TorontoSickKids FoundationMount Sinai Hospital
FundersConnective Tissue Oncology Society
KeywordsMedicineObservational studyContext (archaeology)Medical physicsFamily medicineIntensive care medicinePathology

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.037
metaresearch head score (Gemma)0.077
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: Methods · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: none
Teacher disagreement score0.963
Threshold uncertainty score0.194

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0370.077
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0080.007
Bibliometrics0.0040.004
Science and technology studies0.0000.001
Scholarly communication0.0030.002
Open science0.0030.002
Research integrity0.0030.003
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.668
GPT teacher head0.538
Teacher spread0.130 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designTheoretical or conceptual
DomainMethods
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations27
Published2022
Admission routes1
Has abstractno

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